SPINE - disc herniation

Question 1

Recovery of ambulation in small, nonbrachycephalic dogs after conservative management of acute thoracolumbar disk extrusion is associated with MRI degre resolution of the compression

Answer 1

No

Question 2

What are the 3 MRI signs suggestive of PMM?

Answer 2

Length of T2-weighted hyperintense spinal cord change
HASTE signal loss
Shorter compressive lesions (possible role of more severe focal pressure at the extrusion site)

A segment of total loss of contrast enhancement in the venous sinuses and meninges was more common in the PMM group and the difference approached significance

Question 3

retrogene responsible for IVD degeneration?

Answer 3

FGF4L2, chromosome 12

The presence of 1 or 2 FGF4L2 copies in the absence of the FGF4L1 retrogene has an additive effect on the number of calcified IVD and a minor effect on vertebral geometry in NSDTR dogs. Data support the use of FGF4L2 phenotyping to reduce clinical disease in segregating breeds and to monitor the introduction of wild-type alleles into fixed breed populations.

Question 4

hydromyelia is
1. cranial/caudal to IVDE
2. associated with

Answer 4

mostly cranial, acute lesions

Question 5

Describe what are cervical jerks? What is the most common location of IVDE associated with cervical jerks?

Answer 5

Cervical jerk associated with cervical pain or myelopathy may represent myoclonus
Exclusively secondary to cranial cervical IVDE (50%: C2-C3)