Specific toxicity treatments (Pg. 239) - C

Question 1

TOX t/t - Acetaminophen

Answer 1

N-acetylcysteine (replenishes glutathione)

Question 2

TOX t/t - AChE inhibitors, organophosphates

Answer 2

Atropine > pralidoxime

Question 3

TOX t/t - Antimuscarinic, anticholinergic agents

Answer 3

Physostigmine, control hyperthermia

Question 4

TOX t/t - Arsenic

Answer 4

Dimercaprol, succimer

Question 5

TOX t/t - Benzodiazepines

Answer 5

Flumazenil

Question 6

TOX t/t - β-blockers

Answer 6

Atropine, glucagon

Question 7

TOX t/t - Carbon monoxide

Answer 7

100% O2, hyperbaric O2

Question 8

TOX t/t - Copper

Answer 8

Penicillamine, trientine (Copper penny)

Question 9

TOX t/t - Cyanide

Answer 9

Nitrite + thiosulfate, hydroxocobalamin

Question 10

TOX t/t - Digitalis (digoxin)

Answer 10

Anti-dig Fab fragments

Question 11

TOX t/t - Heparin

Answer 11

Protamine sulfate

Question 12

TOX t/t - Iron

Answer 12

Deferoxamine, deferasirox, deferiprone

Question 13

TOX t/t - Lead

Answer 13

EDTA, dimercaprol, succimer, penicillamine

Question 14

TOX t/t - Mercury

Answer 14

Dimercaprol, succimer

Question 15

TOX t/t - Methanol, ethylene glycol (antifreeze)

Answer 15

Fomepizole > ethanol, dialysis

Question 16

TOX t/t - Methemoglobin

Answer 16

Methylene blue, vitamin C

Question 17

TOX t/t - OpiOids

Answer 17

NalOxOne

Question 18

TOX t/t - Salicylates

Answer 18

NaHCO3 (alkalinize urine), dialysis

Question 19

TOX t/t - TCAs

Answer 19

NaHCO3

Question 20

TOX t/t - Warfarin

Answer 20

Vitamin K (delayed effect), fresh frozen plasma (immediate)