Cytochrome P-450 interactions (Pg. 243) - C

Question 1

CYP450 Inducers (+)

Answer 1

“Chronic alcoholics Steal Phen-Phen and Never Refuse Greasy Carbs”

• Chronic alcohol use
• St. John’s wort
• Phenytoin
• Phenobarbital
• Nevirapine
• Rifampin
• Griseofulvin
• Carbamazepine

Question 2

CYP450 Substrates

Answer 2

“Always Think When Outdoors”

• Anti-epileptics
• Theophylline
• Warfarin
• OCPs

Question 3

CYP450 Inhibitors (-)

Answer 3

“SICKFACES.COM”

• Sodium valproate
• Isoniazid
• Cimetidine
• Ketoconazole
• Fluconazole
• Acute alcohol abuse
• Chloramphenicol
• Erythromycin (macrolides)
• Sulfonamides
• Cipro oxacin
• Omeprazole
• Metronidazole