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First Aid 2018 USMLE Step 1 - Tables/Graphs/Equations/Mnemonics > Autoantibodies (Pg. 111) - C > Flashcards

Autoantibodies (Pg. 111) - C Flashcards

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USMLE® Step 1 flashcards
1
Q

Anti-ACh receptor

A

Myasthenia gravis

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2
Q

Anti-glomerular basement membrane

A

Goodpasture syndrome

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3
Q

Anti-β2 glycoprotein

A

Antiphospholipid syndrome

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4
Q

Anticardiolipin, lupus anticoagulant

A

SLE, antiphospholipid syndrome

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5
Q

Anticentromere

A

Limited scleroderma (CREST syndrome)

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6
Q

Anti-desmoglein (anti-desmosome)

A

Pemphigus vulgaris

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7
Q

Anti-glutamic acid decarboxylase, islet cell cytoplasmic antibodies

A

Type 1 diabetes mellitus

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8
Q

Anti-hemidesmosome

A

Bullous pemphigoid

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9
Q

Antisynthetase (eg, anti-Jo-1), anti-SRP, anti- helicase (anti-Mi-2)

A

Polymyositis, dermatomyositis

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10
Q

Antimicrosomal, antithyroglobulin, anti-thyroid peroxidase

A

Hashimoto thyroiditis

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11
Q

Antimitochondrial

A

1° biliary cirrhosis

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12
Q

Antiparietal cell, anti-intrinsic factor

A

Pernicious anemia

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13
Q

Antiphospholipase A2 receptor

A

1° membranous nephropathy

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14
Q

Anti-Scl-70 (anti-DNA topoisomerase I)

A

Scleroderma (diffuse)

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15
Q

Anti-smooth muscle

A

Autoimmune hepatitis type 1

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16
Q

Anti-SSA, anti-SSB (anti-Ro, anti-La)

A

Sjögren syndrome

17
Q

Anti-TSH receptor

A

Graves disease

18
Q

Anti-presynaptic voltage-gated calcium channel

A

Lambert-Eaton myasthenic syndrome

19
Q

IgA anti-endomysial, IgA anti-tissue transglutaminase

A

Celiac disease

20
Q

MPO-ANCA/p-ANCA

A

Microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome), ulcerative colitis

21
Q

PR3-ANCA/c-ANCA

A

Granulomatosis with polyangiitis (Wegener)

22
Q

Rheumatoid factor (IgM antibody against IgG Fc region), anti-CCP (more speci c)

A

Rheumatoid arthritis

23
Q

Antinuclear (ANA)

A

Nonspecific screening antibody, often associated with SLE

24
Q

Anti-dsDNA, anti-Smith

A

SLE

25
Q

Anti-histone

A

Drug-induced lupus

26
Q

Anti-U1 RNP (ribonucleoprotein)

A

Mixed connective tissue disease

First Aid 2018 USMLE Step 1 - Tables/Graphs/Equations/Mnemonics (81 decks)

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