Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

First Aid 2018 USMLE Step 1 - Tables/Graphs/Equations/Mnemonics > Drug reactions (Pg. 239) > Flashcards

Drug reactions (Pg. 239) Flashcards

You may prefer our related Brainscape-certified flashcards:
USMLE® Step 1 flashcards
1
Q

S/E - Coronary Vasospasm

A

Amphetamin, cocaine, ergot alkaloids, sumatriptan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

S/E - Cutaneous flushing

A

Vancomycin, Adenosine, Niacin, Nitrates, Ca2+ channel blockers, Echinocandins (VANNCE)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

S/E - Dilated cardiomyopathy

A

Anthracyclines (eg, doxorubicin, daunorubicin); prevent with dexrazoxane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

S/E - Torsades de pointes

A

AntiArrhythmics (class IA, III), antiBiotics (eg, macrolides), anti“C”ychotics (eg, haloperidol), antiDepressants (eg, TCAs), antiEmetics (eg, ondansetron) (ABCDE)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

S/E - Adrenocortical insufficiency

A

HPA suppression 2° to glucocorticoid withdrawal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

S/E - Diabetes insipidus

A

Lithium, demeclocycline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

S/E - Hot flashes

A

Tamoxifen, clomiphene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

S/E - Hyperglycemia

A

“Taking Pills Causes Nasty Hyperglycemia”
Tacrolimus, Protease inhibitors, Niacin, HCTZ,
Corticosteroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

S/E - Hypothyroidism

A

Lithium, amiodarone, sulfonamides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

S/E - SIADH

A

Carbamazepine, Cyclophosphamide, SSRIs Can’t Concentrate Serum Sodium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

S/E - Acute cholestatic hepatitis, jaundice

A

Erythromycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

S/E - Diarrhea

A

Acamprosate, acarbose, cholinesterase inhibitors, colchicine, erythromycin, ezetimibe, metformin, misoprostol, orlistat, pramlintide, quinidine, SSRIs
(AACCEEMM -OPQSS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

S/E - Focal to massive hepatic necrosis

A

Liver “HAVAc”

  • Halothane
  • Amanita phalloides (death cap mushroom)
  • Valproic acid
  • Acetaminophen
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

S/E - Hepatitis

A

Rifampin, isoniazid, pyrazinamide, statins, fibrates (Antimycobacterial drugs vs. Lipid lowering agents)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

S/E - Pancreatitis

A

“Drugs Causing A Violent Abdominal Distress”

  • Didanosine, Corticosteroids, Alcohol, Valproicacid, Azathioprine, Diuretics (furosemide, HCTZ)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

S/E - Pill-induced esophagitis

A

Bisphosphonates, ferrous sulfate, NSAIDs, potassium chloride, tetracyclines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

S/E - Pseudomembranous colitis

A

Ampicillin, cephalosporins, clindamycin, fluoroquinolones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

S/E - Agranulocytosis

A

“Can Cause Pretty Major Collapse of Granulocytes”

  • Clozapine, Carbamazepine, Propylthiouracil, Methimazole, Colchicine, Ganciclovir
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

S/E - Aplastic anemia

A

“Can’t Make New Blood Cells Properly”

  • Carbamazepine, Methimazole, NSAIDs, Benzene, Chloramphenicol, Propylthiouracil
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

S/E - Direct Coombs-positive hemolytic anemia

A

Methyldopa, penicillin

21
Q

S/E - Drug reaction with eosinophilia and systemic symptoms (DRESS)

A

Allopurinol, anticonvulsants, antibiotics, sulfa drugs

Potentially fatal delayed hypersensitivity reaction. Latency period (2–8 weeks) followed by fever, morbilliform skin rash, and frequent multiorgan involvement. Treatment: withdrawal of offending drug, corticosteroids.

22
Q

S/E - Gray baby syndrome

A

Chloramphenicol

23
Q

S/E - Hemolysis in G6PD deficiency

A

“Hemolysis IS D PAIN”

  • Isoniazid, Sulfonamides, Dapsone, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin
24
Q

S/E - Megaloblastic anemia

A

“You’re having a mega blast with PMS”

  • Hydroxyurea, Phenytoin, Methotrexate, Sulfa drugs
25
Q

S/E - Thrombocytopenia

A

Heparin

26
Q

S/E - Thrombotic complications

A

Combined oral contraceptives, hormone replacement therapy, SERMs (eg, tamoxifen, raloxifene, clomiphene)

(Estrogen-mediated S/E)

27
Q

S/E - Fat redistribution

A

“Fat PiG”

  • Protease inhibitors, Glucocorticoids
28
Q

S/E - Gingival hyperplasia

A

Phenytoin, Ca2+ channel blockers, cyclosporine

29
Q

S/E - Hyperuricemia (gout)

A

“Painful Tophi and Feet Need Care”

  • Pyrazinamide, Thiazides, Furosemide, Niacin, Cyclosporine
30
Q

S/E - Myopathy

A

Statins, fibrates, niacin, colchicine, daptomycin, hydroxychloroquine, interferon-α, penicillamine, glucocorticoids

31
Q

S/E - Osteoporosis

A

Corticosteroids, depot medroxyprogesterone acetate, GnRH agonists, aromatase inhibitors, anticonvulsants, heparin

32
Q

S/E - Photosensitivity

A

“SAT For Photo”

  • Sulfonamides, Amiodarone, Tetracyclines, 5-FU
33
Q

S/E - Rash (Stevens- Johnson syndrome)

A

“Steven Johnson has epileptic allergy to sulfa drugs and penicillin”

  • Anti-epileptic drugs (especially lamotrigine), allopurinol, sulfa drugs, penicillin
34
Q

S/E - SLE-like syndrome

A

Having lupus is “SHIPP-E”

  • Sulfa drugs, Hydralazine, Isoniazid, Procainamide, Phenytoin, Etanercept
35
Q

S/E - Teeth discoloration

A

“Teethracyclines”

  • Tetracyclines
36
Q

S/E - Tendonitis, tendon rupture, and cartilage damage

A

Fluoroquinolones

37
Q

S/E - Cinchonism

A

Quinidine, quinine

Can present with tinnitus, hearing/vision loss, psychosis, and cognitive impairment

38
Q

S/E - Parkinson-like syndrome

A

“Cogwheel rigidity of ARM”

  • Antipsychotics, Reserpine, Metoclopramide
39
Q

S/E - Seizures

A

“With seizures, I BITE my tongue”

  • Isoniazid (vitamin B6 deficiency), Bupropion, Imipenem/cilastatin, Tramadol, Enflurane
40
Q

S/E - Tardative dyskinesia

A

Antipsychotics, metoclopramide

41
Q

S/E - Fanconi syndrome

A

Cisplatin, ifosfamide, expired tetracyclines, tenofovir

42
Q

S/E - Hemorrhagic cystitis

A

Cyclophosphamide, ifosfamide

Prevent by coadministering with mesna

43
Q

S/E - Interstitial nephritis

A

Penicillins, furosemide, NSAIDs, proton pump inhibitors, sulfa drugs

44
Q

S/E - Dry cough

A

ACE inhibitors

45
Q

S/E - Pulmonary fibrosis

A

“My Nose Cannot Breathe Bad Air”

  • Methotrexate, Nitrofurantoin, Carmustine,
    Bleomycin, Busulfan, Amiodarone
46
Q

S/E - Antimuscurinic

A

Atropine, TCAs, H1-blockers, antipsychotics

47
Q

S/E - Disulfiram-like reaction

A

“Sorry Pals, Can’t Go Mingle”

  • 1st-generation Sulfonylureas, Procarbazine, certain Cephalosporins, Griseofulvin, Metronidazole
48
Q

S/E - Nephrotoxicity/ototoxicity

A

Aminoglycosides, vancomycin, loop diuretics, cisplatin, amphotericin B

Cisplatin toxicity may respond to amifostine.

First Aid 2018 USMLE Step 1 - Tables/Graphs/Equations/Mnemonics (81 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions