Oncogenes (Pg. 218) - C Flashcards
Product / Ass
Oncogene - ALK (Product/Neoplasm)
Product: Receptor tyrosine kinase
Ass: Lung adenocarcinoma
Product / Ass
Oncogene - BCR-ABL (Product/Neoplasm)
Product: Tyrosine kinase
Ass: CML, ALL
Product / Ass
Oncogene - BCL-2 (Product/Neoplasm)
Product: Antiapoptotic molecule (inhibits apoptosis)
Ass: Follicular and diffuse large B cell lymphomas
Product / Ass
Oncogene - BRAF (Product/Neoplasm)
Product: Serine/threonine kinase
Ass: Melanoma, non-Hodgkin lymphoma, papillary thyroid carcinoma
Product / Ass
Oncogene - c-KIT (Product/Neoplasm)
Product: Cytokine receptor
Ass: Gastrointestinal stromal tumor (GIST)
Product / Ass
Oncogene - c-MYC (Product/Neoplasm)
Product: Transcription factor
Ass: Burkitt lymphoma
Product / Ass
Oncogene - HER2/neu (c-erbB2)
Product: Receptor tyrosine kinase
Ass: Breast and gastric carcinomas
Product / Ass
Oncogene - JAK2
Product: Tyrosine kinase
Ass: Chronic myeloproliferative disorders
Product / Ass
Oncogene - KRAS
Product: GTPase
Ass: Colon cancer, lung cancer, pancreatic cancer
Product / Ass
Oncogene - MYCL1
Product: Transcription factor
Ass: Lung tumor
Product / Ass
Oncogene - MYCN
Product: Transcription factor
Ass: Neuroblastoma
Product / Ass
Oncogene - RET
Product: Receptor tyrosine kinase
Ass: MEN 2A and 2B, medullary thyroid cancer
