Somatosensation I Flashcards

1
Q

What are the 5 functions of the somatosensory pathway?

A
→ Conveying sensation from the body
→ touch
→ proprioception ( sense of body position) 
→ Heat and cold
→ pain and itch
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2
Q

How many pairs of spinal nerves do we have?

A

→ 31 pairs

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3
Q

How is the CNS connected to the body?

A

→ Spinal and cranial nerves

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4
Q

What is a nerve?

A

→ a bunch of fascicles

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5
Q

What do fascicles consist of?

A

→ Individual myelinated axons

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6
Q

What is the membrane of the fasciles called?

A

→ perineurium

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7
Q

What is the membrane of the spinal nerve called?

A

→ Epineurium

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8
Q

What is the membrane of each individual axon called?

A

→ Endoneurium

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9
Q

What do the 8 spinal nerves and the top of the thoracic nerves form?

A

→ Brachial plexus

→ Cervical plexus

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10
Q

What is the function of spinal nerves?

A

→ Carry information between the CNS and the periphery

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11
Q

How many pairs of nerves does the cervical region contain?

A

→ 8

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12
Q

How many pairs of nerves does the thoracic region contain?

A

→ 12

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13
Q

How many pairs of nerves does the lumbar region have?

A

→ 5

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14
Q

How many pairs of nerves does the sacral region have?

A

→ 5

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15
Q

How many pairs of nerves does the coccygeal region have?

A

→ 1

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16
Q

What do the dorsal roots contain?

A

→ Sensory afferents

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17
Q

What do the ventral roots contain?

A

→ Motor efferents (somatic)

→ Autonomic effererents

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18
Q

What do dorsal and ventral roots unite to form?

A

→ Spinal nerve

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19
Q

What does white matter contain?

A

→ Ascending and descending axon tracts

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20
Q

What does grey matter contain?

A

→ Cell bodies
→ Dendrites
→ Synapses

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21
Q

Where do the spinal nerves pass through?

A

→ Intervertebral foramina

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22
Q

What do dorsal root ganglia contain?

A

→ All the cell bodies of all the sensory neurons of the somatosensory system

23
Q

What do large fibres sense?

A

→ tactile and proprioceptive

24
Q

What do small fibres sense?

A

→ Temperature
→ pain
→ itch
→ crude touch

25
What are dorsal root ganglia neurons called and why?
→ pseudo unipolar neurons → they have a single process → gives rise to an axon in both directions
26
What kind of adaptation does a Merkel disc have?
→ Slow adapting
27
How many large fibre afferents are there in the skin?
→ 4
28
What kind of touch are Merkels discs sensitive to?
→ Light touch and pressure
29
Where are Meissners corpuscles and Merkels discs located?
→ between the dermis and the epidermis
30
What happens to a Merkels disc if a stimulus is applied and maintained?
→ Action potentials fire | →if the stimulus is maintained then the action potentials continue to fire
31
What happens to a Meissners corpuscle if a stimulus is applied and maintained?
→ action potentials fire | → if the stimulus is maintained the action potentials drop to 0
32
What are the cutaneous tactile afferents?
→ Meissners corpuscles | → Merkels discs
33
What are the deep tactile afferents?
→ Ruffini | → Pacinian
34
What type of fibre are tactile afferents?
→ A beta
35
What do Pacinian corpuscles respond to?
→ Vibration
36
What do Ruffini corpuscles respond to?
→ Slipping | → Non slipping
37
What are fast adapting afferents?
→ Meissner | → Pacinian
38
What are slow adapting afferents?
→ Ruffini | → Merkel
39
What do muscle spindles detect?
→ Changes in muscle length
40
What fibres detect change in length in muscles?
→ Large fibre systems
41
What senses muscle tension?
→ Golgi tendon organs
42
What is muscle length a cue for?
→ Proprioception
43
What type of neuron is a normal motor neuron?
→ Alpha
44
What are A delta fibres like?
→ thin | → myelinated
45
What are C fibres like?
→ Thin | → unmyelinated
46
What does a small receptive field mean?
→ THe stimulus is localised
47
What are the two major somatosensory pathways?
→ Dorsal column - medial lemniscal system | → Spinothalamic tract
48
What does the dorsal column sense?
→ Mediates discriminative touch → vibration → proprioception
49
What does the spinothalamic tract sense?
→ Coarse touch → temperature → pain
50
Describe the pathway from a tactile afferent in the upper body to the somatosensory cortex
→ Stimulus from the Merkel, Ruffini, Pacinian or Meissners occurs → The stimulus travels via 1st order neurons to the dorsal column (cuneatus) → the 1st order neuron travels up to the medulla (nucleus cuneatus) where it synapses with a 2nd order neuron → the 2nd order neuron decussates at the midline → the 2nd order neuron travels up the medial lemniscal tract of the brainstem to the thalamus → 2nd order neuron synapses at the thalamus with a 3rd order neuron which carries it to the somatosensory cortex
51
What is the difference between the Cuneate and Gracile dorsal column?
→ Cuneate - upper body | → Gracile - lower body
52
What inputs come to the ventral posterior medial nucleus?
→ Sensory inputs of the head and face
53
What inputs come to the ventral posterior lateral nucleus?
→ Sensory inputs from the body
54
Where is the somatosensory cortex?
→ Front of the parietal lobe