Motivation Flashcards
What is motivation?
β A physical need
β Wanting/liking something
What does the hypothalamus do?
β Maintain homeostasis by regulating three interrelated functions
What are the 3 things that the hypothalamus controls?
β Endocrine secretion
β Autonomic nervous system
β Emotions and drive
Describe anabolism?
β glucose goes to the liver
β Skeletal muscle stores glucose as glycogen
Describe catabolism?
β Glycogen gets broken down to glucose
What is parabiosis?
β Sharing of blood circulation between animals
What do obese mice not produce?
β leptin
What happens if you connect an ob/ob mouse and a normal mouse via parabiosis?
β the ob/ob mouse will decrease in size
Where does leptin bind?
β Leptin receptors on the arcuate nucleus
When is leptin released and why?
β When you finished eating
β to stop feeding
Where is the hypothalamus?
β At the base of the brain
What happens when you lesion the VMH?
β weight gain
What happens during lateral hypothalamic syndrome?
β Diminished appetite for food
β Anorexia
What happens during ventromedial hypothalamic syndrome?
β Overeating
β Obesity
What are the anorectic peptides?
β Alpha MSH
β CART
Describe the anorexic response?
β Leptin increases in circulation
β Leptin binds to receptors on the arcuate nucleus
β Alpha MSH and CART neurons in arcuate nucleus are activated which project to the lateral hypothalamus
β These neurons release alpha MSH and CART peptides
β Peptides inhibit feeding
Describe how the basal metabolic rate is increased during the anorexic response?
β Leptin stimulates the Alpha MSH and CART neurons of the Arcuate Nucleus.
β These neurons extend from the Arcuate Nucleus to the Paraventricular Nucleus.
β The Paraventricular Nucleus is stimulated and stimulates the release of ACTH and TSH from the Anterior Pituitary.
β ACTH and TSH increases the basal metabolic rate.