skin immunology Flashcards
1
Q
what type of immune cell is a langerhan cell?
A
dendritic cell
2
Q
what do the langerhan cells do?
A
antigen presenting cells (characterized by Birbeck granule)
3
Q
name some immune functions of keratinocytes?
A
produce AMPS which directly kill pathogens
produces cytokines and chemokines
4
Q
what T cells are mainly found in epidermis?
A
CD8+ cells
5
Q
what T cells are found in dermis?
A
both CD4+ and CD8+
6
Q
what other immune cells are found in dermis?
A
macrophages neutrophils mast cells Nk cells dentritic cells
7
Q
what is a type 1 hypersensitivity reaction/
A
allergic reaction IgE mediated
8
Q
what mediates type 4 hypersensitivity reactions?
A
Th1 cells (T cell mediated)
