Pigmented skin lesions Flashcards
what can tumours arise from?
epidermis melanocytes dermis appendages lymphoid elements
what gene determines your pigmentation?
melanocortin 1 receptor gene (MC1R)
what are actinic lentigines also known as?
age or liver spots
what are ephilides?
freckles
is there a risk of melanoma with congenital melanocytic naevi?
YES
when are you likely to get junctional naevus?
childhood
when are you likely to get compound naevus?
adolescence
early adult hood
when are you likely to get intradermal naevus?
adulthood
what are the 2 types of dysplastic naevi?
sporadic famial
is the epidermis affected by dysplastic naevi?
no
peripheral halo of pigmentation
halo naevi
entirely dermal
pigment rich with dentritic spindle cells
mimic melanoma
blue naevi
mimic melanoma
benign
large spindle and or epitheloid cells
spits naevi
is malignant melanoma more common in males or females?
females
change in shape bleeding irregular pigmentation satellite nodules ulceration new pigmented lesion
suspect melanoma
what are the 4 main types of melanoma?
superficial spreading
acral/mucosal- palm soles, under nails
lentigo maligna
nodular
where does melanoma spread to?
brain liver Gi tract lungs heart skin and soft tissues
melanoma treatment
excision