skin

Question 1

s.basale

Answer 1

cell division (stem cells)

Question 2

S.spinosum

Answer 2

keratin intermediate filament linkage via desmosomes

Question 3

S.granulosum

Answer 3

keratohyaline granules - keratin aggregation

Question 4

S. lucidum

Answer 4

specialised cell death programme

Question 5

s.conreum

Answer 5

water proof cell ghosts

Question 6

fillagrin

Answer 6

found in the granules of keratohyline molecules

Question 7

function of fillagrin?

Answer 7

• maintain optimal skin barrier
• aid keratin aggregation
• inhibits water loss

Question 8

how long does it take cells to get from the bottom to top

Answer 8

about a month

Question 9

what will anchor basal cells to the basal lamina

Answer 9

hemidesmesomes

Question 10

what will anchor the dermis to the basal lamina

Answer 10

collagen VII

Question 11

mutated collagen VII

Answer 11

dystrophic epidermolysis bullosa

Question 12

how is melanin transferred to keratinocytes?

Answer 12

melanocytes synthesis melanosomes and then they transfer by exocytosis/endocytosis to keratinocytes

Question 13

where are you most likely to find langerhans cells

Answer 13

s.spinosum

Question 14

what type of granules does langerhans cells have?

Answer 14

birbeck granules

Question 15

dermal epidermal junction

Answer 15

• complex that prevents sheering
• where the dermis and epidermis meet

Question 16

papillary dermis

Answer 16

comprises of fine collagen and elastic fibres, small blood vessels and nerves

Question 17

reticular dermis

Answer 17

comprises of coarser collagen and elastic fibres and larger blood vessels and nerves

Question 18

mammary glands

Answer 18

modified apocrine glands - lactation under hormonal control

Question 19

nails

Answer 19

nail plate formed from keratin, growth from nail nail which passes into dermis

Question 20

teeth

Answer 20

enamel of the teeth develops from epithelium