Skeletal System (A&P Bootcamp hiegh yield) Flashcards

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1
Q

5 types of Bone

A
  1. long bones
  2. short bones
  3. flat bones
  4. sesamoid bones
  5. Irregular bones
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2
Q

Long bones

A

made of cortical bone(compact) and pockets of cancellous bone(spongy). Important features include the epiphysis, diaphysis, medullary cavity, metaphysis, and epiphyseal plate.

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3
Q

Epiphysis

A

end of a long bone that forms
joints with other bones and contains red
bone marrow for hematopoiesis (blood
cell synthesis).

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4
Q

Diaphysis

A

long hollow shaft in center of
bone.

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5
Q

Medullary cavity

A

located within the
diaphysis and contains red and yellow
bone marrow (area of fat storage).

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6
Q

Metaphysis

A

similar to epiphyses and
found between the medullary cavity and
epiphyseal plates.

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7
Q

Epiphyseal plate

A

“growth plate” located
between epiphysis and metaphysis. Made
out of hyaline cartilage and works to
lengthen the diaphysis through growth and
ossification .

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8
Q

Short bones

A

as wide as they are long and
mainly provide support (eg. parts of the
wrist).

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9
Q

Flat bones

A

mainly provide protection (eg.
skull).

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10
Q

Sesamoid bones

A

found within tendons to
help muscles pull (eg. kneecap).

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11
Q

irregular bones

A

irregularly shaped (eg.
pelvis).

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12
Q

Cortical bone

A

is the dense outer layer of bone that
supports the weight of our bodies. It is composed
of many microstructures: Osteons, Haversian canals, Lamellae, Lacunae, Canaliculi, Volkmann’s canals

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13
Q

Osteons

A

cortical bone’s functional unit,
composed of tiny multi-layered cylinders.
Also known as haversian systems because
they contain a haversian canal in their center.

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14
Q

Haversian canals

A

‘tubes’ that contain blood
vessels for nutrient supply.

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15
Q

Lamellae

A

layers of the osteon.

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16
Q

Lacunae

A

small spaces between lamellae that
hold bone cells and interconnect through
canaliculi .

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17
Q

Canaliculi

A

small channels that connect
lacunae and the haversian canal.

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18
Q

Volkmann’s canals

A

connect Haversian canals
to the periosteum , which provides nutrients.

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19
Q

Cancellous bone

A

is the spongy inner layer of bone
that soaks up red bone marrow via a web of
trabeculae (connective tissue that supports
cancellous bone).

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20
Q

Bone remodeling

A

is the process of going back and
forth between the processes of ossification (bone
formation) and resorption (bone loss).

21
Q

Types of cells

A

Osteoprogenitors
Osteoblasts
Osteocytes
Osteoclasts

22
Q

Osteoprogenitors

A

immature precursor cells
that differentiate into osteoblasts .

23
Q

Osteoblasts

A

build bone by secreting
proteins and utilizing blood calcium. They
mature into osteocytes after getting trapped
inside the bone matrix they create.

24
Q

Osteocytes

A

live in lacunae in osteons to
maintain bone.

25
Q

Osteoclasts

A

eat and resorb bone, bringing
calcium back into the blood. Derived from
monocytes .

26
Q

Mechanisms involved in bone remodeling

A

Parathyroid hormone
Vitamin D
Calcitonin

27
Q

Parathyroid hormone

A

increases blood calcium levels by stimulating osteoclasts and depressing osteoblasts . Secreted by the
parathyroid gland .

28
Q

Vitamin D

A

increases blood calcium levels by raising intestinal calcium absorption. Activated by parathyroid hormone, but provides negative feedback on PTH production.

29
Q

Calcitonin

A

decreases blood calcium levels by depressing osteoclasts , allowing osteoblasts to build bone without competition. Secreted by parafollicular cells (C cells) of the thyroid gland .

30
Q

Osteoid

A

is the organic component of bone
containing many proteins such as collagen (gives bone tensile strength).

31
Q

Hydroxyapatite

A

is the inorganic mineral component of bone that gives the bone density and strength.

32
Q

Two types of embryonic ossification:

A

Intramembranous ossification
Endochondral ossification

33
Q

Intramembranous ossification

A

bone is created directly within fibrous membranes, mainly for flat bones . Osteoblasts start by secreting osteoid, which hardens and houses osteocytes. Eventually, cortical bone is created.

34
Q

Endochondral ossification

A

bone is created indirectly through a cartilage model, mainly for long bones . The cartilage model calcifies during fetal development, creating ossification centers that help form the features of long bones.

35
Q

Types of connective tissue:

A

Fibrous connective tissue
Cartilage
Joints

36
Q

Fibrous connective tissue

A

has a matrix made up of fibers.
Ex tendons, ligaments, periosteum, endosteum

37
Q

Tendons

A

connect muscle to bone.

38
Q

Ligaments

A

connect bone to bone.

39
Q

Periosteum

A

membrane that covers cortical bone with an outer fibrous layer (vascularized) and an inner/cambium layer (collagen for attachment to cortical bone)

40
Q

Endosteum

A

membrane located between cortical and cancellous bone.

41
Q

Cartilage

A

is avascular (lacks blood vessels) and is not innervated (as opposed to bone which is highly vascular and innervated).

42
Q

Chondroblasts

A

build cartilage by secreting collagen and elastin.
Hyaline cartilage
Fibrous cartilage
Elastic cartilage

43
Q

Hyaline cartilage

A

slightly flexible and important in providing support and stability to joints.

44
Q

Fibrous cartilage

A

high rigidity and resists tension, found in intervertebral discs and knee meniscus.

45
Q

Elastic cartilage

A

highly flexible and found in ears and epiglottis.

46
Q

Joints

A

are vascularized and innervated. They
are found between bones. Below are types of joints.
Synarthroses
Amphiarthroses
Diarthroses

47
Q

Synarthroses joints

A

dense, fibrous joints that do not move.

48
Q

Amphiarthroses joints

A

cartilaginous joints that partially move.

49
Q

Diarthroses

A

synovial joints that fully move. Typically contain hyaline cartilage .