skeletal system Flashcards
functions of skeletal system
support
protection
movement
red blood cell and hormone production
mineral, growth factor, and fat storage
long bone
femur
flat bone
skull
short bone
metacarpals
irregular bone
vertebrae
sesamoid bone
patella
red bone marrow
red blood cell production
yellow bone marrow
stores fat
compact bone
dense outer layer
smooth and solid
contains osteons
found in the diaphyses of long bones
majority of skeleton
gives strength and support
stores calcium
spongy bone
honeycomb of flat pieces of bone deep to compact bone (trabeculae)
found at the ends of long bones, ribs, skull, pelvis, and vertebrae
helps make bones lighter
volkman’s cannal
connects blood vessels and nerves of the periosteum, medullary cavity, and central canal
runs perpendicular
lamellae
bony layers of osteon
collagen fibers allow resistance to twisting
canaliculi
tiny canals in osteon that connect lacunae to each other and central canal
osteocyte
mature bone cell that monitors and maintains the mineralized bone matrix
osteonic canal
aka haversian canal
houses blood vessels, lymphatic vessels, and nerves
runs parallel
osteoblasts
matrix synthesizing cell responsible for bone growth
osteoclasts
bone resorbing cell
intramembranous ossification
bone develops from fibrous membranes (flat bones)
osteoid is secreted by osteoblasts within the fibrous membrane and calcifies
spongy bone and periosteum form
compact bone replaces spongy bone
red marrow in spongy bone appears
endochondral ossification
bone formed by replacing hyaline cartilage (long bone)
interstitial growth
allows increase in the length of long bones
appositional growth
allows increase in bone thickness
osteoblasts beneath periosteum secrete bone matrix on external bone
osteoclasts remove bone on endosteal surface
importance of calcium
nerve transmission
muscle contraction
blood coagulation
cell division
secretion of glands and nerve cells
bone remodeling
in response to stress or hormones
growth hormone
most important in stimulating epiphyseal plate activity in infancy and childhood
sex hormones
promotes adolescent growth spurts
end growth by inducing epiphyseal growth closure (epiphyseal line)
PTH
resorption of Ca2+
releases more calcium
calcitonin
removes blood Ca2+ levels temporarily if in high doses
rickets
bowed legs caused by vit. D deficiency or Ca2+
osteomalacia
bones poorly mineralized
inadequate Ca2+ salts
soft and weak bones
osteoporosis
bone resorption outpaces deposit
kyphosis
excessive curvature of spine
lordosis
excessive curvature of the lower portion of the spine
scoliosis
sideway curvature of the spine
herniated disk
a rupture b/w the rubbery cushions b/w the vertebrae
axial
long axis of the body
skull, veretebral column, rib cage
appendicular
bones of the upper and lower limbs
girdles attaching limbs to axial skeleton
open fracture
aka compound fracture
skin is penetrated
closed fracture
aka simple fracture
skin is not penetrated
nondisplaced fracture
ends retain normal position
displaced fracture
ends outside of normal position
complete fracture
broken all the way through
incomplete fracture
not broken all the way through
comminuated fracture
bone fragments into 3 or more pieces
compression fracture
bone is crushed
spiral fracture
ragged break due to excessive twisting force
epiphyseal fracture
epiphysis separates from diaphysis
depressed fracture
broken bone portion is pressed inward
greenstick fracture
incomplete fracture most common in children
closed reduction
realignment of bone w/o surgery
open reduction
realignment of bone involving surgery
immobilization
braces or casts can help in immobilization of the joints for treating a fracture
sharpey’s fibers
secure to bone matrix
osteogenic layer
contains osteogenic cells (primitive stem cells)
periosteum
outer fibrous layer of dense irregular CT
osteogenic cells
mitotically active stem cells in periosteum and endosteum
aka osteoprogenitor cells
osteoblasts
secrete osteoid
compact bone
lamellar bone
red marrow
found within trabeculae and dipole
in medullary cavities in newborns
long bone have little red marrow (heads of femur and humerus only)
epiphyseal plate closure
18 years (females)
21 years (males)
mechanical stress
controls where bone remodeling takes place
hormones
controls whether and when bone remodeling takes place
hematoma formation
- hematoma forms
- soft callus forms
- bony callus forms
- bone remodeling occurs
drugs that treat osteoporosis
biphosphonates
selective estrogen receptor modulators
statins
denosumab
paget’s disease
high ratio of spongy to compact bone
poorly mineralized
usually in spine, pelvis, and skull
treated calcitonin and biphosphonates
osteomyelitis
leukocytes enter
release lytic enzymes
pus spreads to impair local blood flow (sequestra)
involucrum (new bone formation)
leptin
hormone released by adipose tissue
role in bone density regulation
inhibits osteoblasts