heart Flashcards
murmur
sound of blood flowing through a valve
mitral valve stenosis
narrowing of a valve due to Ca2+ deposits or endocarditis
leads to impaired BF from left atrium to left ventricle
increased generated force leads to left atrium hypertrophy and enlargement
treated via BB, CCB, surgery
symptoms include DOE, fatigue, loud S1, mid-diastolic murmur
mitral valve prolapse
blood backflows into the mitral valve and back into the left atrium
reduces CO
may cause pulmonary hypertension
ischemia
heart is deprived of O2
leads to anaerobic respiration and lactic acid buildup
high Ca2+ and H+ conc.
can lead to mitochondria damage and closing of gap junctions
anoxia
deficiency or complete loss of O2 in other tissues of the body
angina pectoralis
chest pain
treated via nitroglycerin (vasodilator), BB, ballon angioplasty/stents
myocardial infraction
aka “heart attack”
Bf to the heart is stopped can be diagnosed via EKG, blood tests, angiogram, echocardiogram
treated via asprin, plavix, BB, surgery
CHF
heart has reduced ability to pump blood
long-term condition
can cause edema to the lower portions of the body
risk factors of myocardial infraction and angina pectoralis
hypertension
dyslipidemia
smoking
P-Q interval
time it takes atria to depolarize
Q-T interval
time it takes ventricles to depolarize and repolarize
flutter
rapid, regular contractions that can later progress to fibrillation
fibrillation
rapid, irregular contractions that can impair pumping of blood and cease circulation
can lead to brain death
heart block
few, or no impulses reach the ventricles, causing them to contract slowly
ventricular filling
mid-late diastole
AV valves open and ventricles start filling w/ blood due to the atria contracting
when pressure of the ventricles exceed the atria the AV valves close
isovolumetric contraction
ventricular systole
all valves closed
volume of blood stays the same
atria relax
ventricles contract
increase in pressure
ventricular ejection
when the pressure in the ventricle exceeds the pressure in the aorta and pulmonary arteries ventricular ejection occurs
isovolumetric relaxation
early diastole
SL valves close
pressure decreases
CO
amount of blood the. heart pumps in 1 min
HR*SV
SV
amount of blood pumped out of one ventricle w/ each beat
EDV-ESV
frank-sterling law
increase in stretch of the heart-> increases contraction size-> increases CO
increase in EDV leads to increase in SV
fibrous pericardium
protects
anchors to surrounding structures
prevents overfilling
myocardium
made up of spiral bundles of contractile cardiac muscle cells and a cardiac skeleton which had interlacing layers of CT
endocardium
made of simple squamous epithelium
continuous w/ the endothelial linings of blood vessels and lines heart chambers and the cardiac skeleton of valves as well
cardiac skeleton
anchor cardiac muscle fibers
support vessels and valves
limit the spread of APs to specific paths
left coronary artery
receive blood from aortic SL valve
branches into circumflex, left marginal, and LAD arteries
right coronary artery
receives blood from pulmonary SL valve
branches into right marginal and PAD arteries
incompetent valve
blood backflows so heart repumps same blood over and over
valvular stenosis
stiff flaps-> constrict opening
heart must exert more force to pump blood
cardiac tamponade
excess fluid sometimes compresses heart->limits pumping ability
col pulmonale
enlargement of the right ventricle
due to increased BP in pulmonary circuit
hypocalcemia
depresses heart
hypercalcemia
increased HR and contractility
hyperkalemia
alters electrical activity
can lead to heart block and cardiac arrest
hypokalemia
feeble heartbeat
arrhythmias
pulmonary congestion
left side fails
blood backs up into lungs
peripheral congestion
right side fails
blood pools in body organs
leads to edema
treatment for pulmonary and peripheral congestion
diuretics
vasodilators
digitalis
coronary sinus
branches into great, middle, and small cardiac veins
empties into right atrium
preload
degree of stretch of cardiac muscle cells before they contract
measures by EDV
contractility
contractile strength
afterload
pressure ventricles must overcome to eject blood
hypertension increases after load
female HR
faster than males
desmosomes
prevent cells from separating during contraction
inotrophic effect
affects contractility
due to medications
can be positive or negative