SIDS

Question 1

Definition

Answer 1

sudden death of an infant
under one year of age
which remains unexplained after thorough case investigation - including performance of a complete autopsy, examination of death scene, and a review of clinical history

Question 2

Triple risk model

Answer 2

critical development
vulnerable infant
stressor

Question 3

Macroscopic findings

Answer 3

Petechial haemorrhages
pulmonary edema and or congestion
cerebral edema and or congestion

Question 4

Microscopic findings

Answer 4

signs indicative of chronic hypoxia or hyperaemia

Question 5

Etiology

Answer 5

chronic hypoxia/hypoxaemia 
brain stem immaturity 
neurochemical deficiency 
prone sleeping position 
cardiac remodelling/conduction LQTS

Question 6

Differential diagnosis

Answer 6

cardiac - congenital valve lesions, myocarditis, channelopathies, fibro-elastosis

pulmonary - pneumonitis, bronchiolitis, etc

brain - meningitis , encephalitis, A-V malformation

trauma, poisoning, hepatitis, enterocolitis, sepsis, aspiration, heat illness, hyperthermia