Jaundice Flashcards
1
Q
Non physiologic jaundice
A
onset before 24 hours rise > 8.5 mmol/l/h signs of underlying illness - vomiting, lethargy, poor feeding, excessive weight loss, apnoea, tachypnoea, temp instability > 8d term, 14d premature direct bilirubin > 34 mmol/l at any time
2
Q
Prolonged Cholestatic jaundice
> 14 days
A
Conjugated fraction greater 20% total bilirubin
hepatobiliary dysfunction
obstructive - biliary atresia, choledochal cyst, CF
hepatocellular - viral CMV, HIV, UTI, sepsis
genetic/metabolic - a-antitrypsin deficiency, tyrosinaemia, galactosaemia, hypothyroidism, CF
toxic, secondary - TPN, drugs, toxins, shock, hypo perfusion
