Antibiotic use Flashcards
1
Q
Before initiate treatment?
A
- Host factors to be considered - age, history allergy recent AB use etc
- Site of infection - con greater than or equal to MIC
- What do you start - 24-72 hours lag in results
empiric treatment - broad spectrum and definitive therapy - de-escalation
2
Q
De-escalation options
A
Decrease number/spectrum
Shorten duration
Discontinue
3
Q
MIC
A
minimum inhibitory concentration
lowest concentration that will inhibit organism growth
4
Q
Bactericidal
A
target cell wall, cell membrane, bacterial DNA
cause cell death
5
Q
Bacteriostatic
A
inhibit bacterial replication without killing organism
target protein synthesis
6
Q
Pharmacokinetics
A
what the body does to the drug
absorption, distribution, metabolism, elimination
7
Q
Pharmacodynamics
A
what the drug does to the body
8
Q
Nosocomial infections
A
Infection follows 48 hours AFTER medical contact ESKAPE organisms Enterococcus faecium Staphylococcus aureus Klebsiella Acinetobacter baumannii Pseudomonas aeruginosa Enterobacter
9
Q
IPC
A
Infection prevention and control aims prevent/ control the spread of infections in healthcare facilities and the community
Goal
- prevent susceptible patients acquiring pathogenic MO
- limit spread antimicrobial resistant infections
10
Q
Stewardship
A
Any activity promotes
- use of antimicrobial only when indicated
- appropriate selection of antimicrobials
- appropriate dosing of antimicrobials
- appropriate route and duration antimicrobial therapy
