Sex Cord Ovarian Tumours

Question 1

Examples of Sex Cord- stromal tumours?

Answer 1

Fibroma/ Theca (most common)
Granulosa Cell tumour
Sertoli- Leydig Cell Tumours

Question 2

Are sex cord stromal tumours common?

Answer 2

no- rare

Question 3

are epithelial or sex cord stromal tumours more agressive?

Answer 3

epithelial tumours are more agressive

Question 4

what are sex cord stromal tumours?

Answer 4

Tumours that arise from stroma (connective tissue) or sex cords. (embryonic structures associated with follicles)

Can be benign or malignant
-less aggressive than epithelial tumours

Question 5

what is the most common sex cord stromal tumour?

Answer 5

fibroma/ theca

Question 6

fibroma/ theca
-benign or malignant?

Answer 6

benign

Question 7

presentation of someone with fibroma/theca and why?

Answer 7

Tumour may produce oestrogen causing uterine bleed

Question 8

how does a fibroma/theca look when it is cut into?

Answer 8

Solid tumour, looks like a potato when cut into

Question 9

investigations for fibroma/ theca?

Answer 9

-need to do biopsy to exclude Rare form of fibrosarcoma

Question 10

what do granulosa cells make up?

Answer 10

corpus luteum and line the follicles

Question 11

are granulosa cell tumours benign or malignant?

Answer 11

all are potentially malignant

Question 12

what may Sertoli- Leydig cell tumours produe?

Answer 12

androgens

Question 13

commonest place for cancer to metastasise from to reach the ovaries?

Answer 13

METASTATIC TUMOURS
-must be considered in all cases, especially when tumours are bilateral and small

Commonest:
-Stomach
-Colon
-Breast
-Pancrease