Epithelial Ovarian Tumours

Question 1

examples of epithelial ovarian tumours?

Answer 1

-Serous
-Clear cell
-Mucinous
-Endometrioid
-Brennar
-Undifferentiated carcinoma

Question 2

Describe a benign epithelial ovarian tumour?

Answer 2

-no cytology abnormalities
-no proliferation
-no stromal invasion

Question 3

describe a borderline epithelial ovarian tumour?

Answer 3

-cytology abnormalities
-proliferation
-no stromal invasion

Question 4

describe a malignant epithelial ovarian tumour?

Answer 4

-stromal invasion

Question 5

how do borderline epithelial tumours spread?

Answer 5

spread on the surface like implants but do not invade deeply like other cancers
-unlikely to spread
-growth more controlled and so better prognosis

Question 6

what is a serous carcinoma of the ovaries?

Answer 6

Malignant type of ovarian epithelial cancer

Question 7

what is the precursor lesion for a high grade serous carcinoma?

Answer 7

Serous tubal intraepithelial carcinoma (STIC)

Question 8

what is the precursor lesion for a low grade serous carcinoma?

Answer 8

Serous borderline tumour

Question 9

where are high grade serous carcinomas usually found?

Answer 9

often tubal

Question 10

what diseases are clear cell carcinomas and endometriod carcinomas commonly associated with?

Answer 10

-Endometriosis of ovaries (mainly endometriod)
-Lynch Syndrome (mainly clear cell carcinoma)

Question 11

are clear cell carcinomas and endometriod carcinomas benign or malignant?

Answer 11

malignant

Question 12

What is a brenner tumour?

Answer 12

-a tumour of transitional type epithelium
-usually it is benign (borderline and malignant variants are very rare)

Question 13

are mucinous tumours usually malignant?

Answer 13

no- 75% are benign