Session 6 - Organ Failure Flashcards
What is the characteristics of blood flow in capillaries?
Cross sectional area is huge
Flow is slow
What are the characteristics of lymphatics?
Blind ended capillaries in the interstitium
Where does the components of the lymph system dump into?
Venous system
What is the characteristics of flow through the lymphatic vessels?
Low pressure, w/ valves
Need muscles contractions to aid in flow
What is the interstitium?
Space between cells and microcirculation
What are the three important tissue components the interstitium responsible for?
Structural + Absorptive + Adhesive
What are the structural components of the interstitium?
Collagen + Elastin
What are the absorptive cells found in the interstitium?
Glycosaminoglycans + Proteoglycans
What are the adhesive cells found within the interstitium?
Fibronectin + Laminin
What % of body weight is fluid?
60%
What % of body weight, from fluid, is found in the ICF?
40%
What are the two components of ECF?
Plasma + Interstitium
What % of body weight, from fluid, is located in the plasma?
4 to 5%
What % of the body weight, due to fluid, is found in the interstitium?
16%
What two hormones does renin stimulate?
Aldosterone + AngII
What does AngII do?
Thirst + ADH release
What does aldosterone do?
Water retention + Potassium loss
What cells release renin?
Juxtaglomerular
What two things does water retention cause?
Increase circulating volume + preload
Increased venous filling
What are the results of increased circulating volume + preload due to water retention?
CO increases
What are the results of increased venous filling pressure due to water retention?
Fluid accumulates in cavities + interstitium
What is triggered (aka what receptors and down stream effects) occur with blood volume expansion?
Arial myocyte stretch
ANP released from heart + brain
Water excretion
What type of receptors stimulate ANP release in the brain?
Baroreceptors
What occurs with hyperosmolarity + dehydratio, in regards to rectors and downstream effects?
Osmoreceptors + Barroreceptors stimulate ADH release + Oxytocin
Water retention + Vasocontriction