Seen component - Q2 Flashcards

1
Q

What is the main goal of blood sugar regulation?

A

To maintain glucose levels within a narrow optimal range (approximately 70–110 mg/dL).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What type of control governs blood sugar regulation?

A

Homeostatic control.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which two endocrine hormones primarily regulate blood sugar?

A
  • Insulin
  • Glucagon
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which organ acts as a central hub for detecting changes in blood glucose?

A

The pancreas.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which part of the pancreas is responsible for endocrine function?

A

The islets of Langerhans.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How do insulin and glucagon influence glucose?

A

They orchestrate its storage, utilization, and production.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which tissues are mainly affected by insulin and glucagon?

A
  • Liver
  • Muscle
  • Adipose tissue
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Why are feedback loops important in blood sugar regulation?

A

They help match metabolic demand and prevent dangerous glucose fluctuations.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Where are the islets of Langerhans located?

A

In the pancreas.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which cells in the pancreas secrete insulin?

A

Beta (β) cells.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which cells secrete glucagon?

A

Alpha (α) cells.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which cells secrete somatostatin?

A

Delta (δ) cells.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What hormone is produced by PP cells?

A

Pancreatic polypeptide.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Where is the pancreas located?

A

Posterior to the stomach in the abdominal cavity.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

In which region of the pancreas are islets most concentrated?

A

The tail region.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Where do islet-secreted hormones drain into?

A

The hepatic portal vein.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Why is the hepatic portal vein important in blood sugar regulation?

A

It allows hormones to act quickly on the liver.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

When is insulin secreted?

A

In response to high blood glucose.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What does insulin promote in muscle and adipose tissue?

A

Glucose uptake.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What process does insulin stimulate in liver and muscle?

A

Glycogenesis.

21
Q

Which liver processes does insulin inhibit?

A
  • Gluconeogenesis
  • Glycogenolysis
22
Q

What effects does insulin have on adipose tissue?

A
  • Promotes lipogenesis
  • Inhibits lipolysis
23
Q

What does insulin enhance besides glucose metabolism?

A
  • Protein synthesis
  • Cell growth
24
Q

When is glucagon secreted?

A

In response to low blood glucose.

25
What processes does glucagon stimulate in the liver?
* Glycogenolysis * Gluconeogenesis
26
What does glucagon promote in adipose tissue?
Lipolysis.
27
How does glucagon act in relation to insulin?
Antagonistically.
28
What happens to blood glucose after a meal?
It rises.
29
What pancreatic cells respond to high blood glucose?
Beta cells.
30
What does insulin do after a meal?
Promotes glucose uptake and storage.
31
What reduces insulin secretion after glucose is lowered?
Negative feedback.
32
What happens to blood glucose during fasting?
It falls.
33
What cells respond to low blood glucose?
Alpha cells.
34
How does the liver respond to glucagon?
Releases glucose via glycogenolysis and gluconeogenesis.
35
Which organs especially rely on glucose during fasting?
Vital organs, especially the brain.
36
Which hormones are released during exercise and stress?
* Catecholamines * Cortisol
37
How do these hormones affect glucose?
Increase blood glucose by stimulating hepatic output and inhibiting insulin action.
38
What role does the liver play in blood sugar regulation?
Stores glycogen and produces glucose.
39
Can skeletal muscle release glucose into the blood?
No, due to lack of glucose-6-phosphatase.
40
What does adipose tissue release during lipolysis?
* Glycerol * Fatty acids
41
How does cortisol affect glucose metabolism?
Enhances gluconeogenesis and reduces peripheral glucose uptake.
42
What are the effects of growth hormone?
* Decreases glucose uptake * Increases lipolysis
43
What type of feedback controls blood sugar?
Negative feedback.
44
What happens when blood glucose is high?
Insulin is released to lower glucose.
45
What happens when insulin lowers blood glucose?
Insulin secretion is reduced.
46
What happens when blood glucose is low?
Glucagon is released.
47
What happens when glucagon raises blood glucose?
Glucagon secretion is reduced.
48
What does this feedback prevent?
Hypoglycemia and hyperglycemia.
49
What overall state is maintained by this mechanism?
Homeostasis.