Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

561 Pharm > Sedatives, Anti-Anxiety, Hypnotics > Flashcards

Sedatives, Anti-Anxiety, Hypnotics Flashcards

1
Q

sedative

A

drug decerasing activity, moderate excitement, calm pt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

hypnotic

A

produces drowsiness, facilitate onset/maintenance of sleep
higher dose causing sleep as compared to lower dose calming

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

anxiolytic

A

anti anxiety
cause calm and quietness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

primary agents of sedative, hypnotic, and anti anxety

A

benzodiazepines
Z drugs
melatonin receptor agonists
orexin receptor antagonist
atypical: buspirone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

benxodiazepines suffixes

A

-azolam
-azepam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

benzodiazepines list

A

sleep:
temazepam
triazolam
estazolam
quazepam
anti anxiety:
diazepam
lorazepam
alpazolam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

benzo MOA

A

potentiate GABA, increasing Cl- channel opening to hyperpolarize and inhibit AP
inhibitory effect on cortex and limbic system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

effects of benzos

A

anxiolysis, anterograde amnesia, sedation, anticonsulsive, antiemesis, muscle relaxation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

side effects of benzos

A

excess sedation
motor impairment
confusion
discontinuation syndrome - rebound insomnia
potentiates CNS depression from alcohol
tolerance
dependence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

benzo drug interactions

A

alc, antihistamines, antipsychotics, opioids, TCAs
cough syrup w alc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

antidote for benzo toxicity

A

flumazenil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Z drugs MOA

A

bind GABA receptors in brain
more selective than benzos

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

list Z drugs

A

zolpidem
zaleplon
eszopiclone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Z drug side effects

A

GI upset
headache
dizziness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

melatonin receptor agonists MOA

A

short term insomnia treatment
melatonin released by pineal gland

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

list melatonin receptor agonists

A

ramelteon
tasimelteon (for non 24 hours sleep disorder)

17
Q

side effects of melatonin receptor agonists

A

headache
dizziness
somnolence
hepatotoxicity for tasmelteon

18
Q

orexin receptor antagonists MOA

A

endogenous neuropeptides activating orexin receptors 1 and 2 in hypothalamus
excitatory, releases NTs for arousal, wakefullness, appetite

19
Q

suvorexant indication

A

insomnia

20
Q

orexin receptor antagonist suffix

A

rexant

21
Q

buspirone MOA

A

partial agonist for serotonin 5 HT1A receptor

22
Q

antidepressants for anxiety

A

SSRIs
SNRIs
TCAs

23
Q

implications for PT and sedative/anti anxiety, hypnotics

A

schedule therapy accounting fot hangover effect
reduced ability to follow commands
weakness
decreased response time
decreased motor control
sleep disturbance
benefit of calm/relaxation
decreased ability to participate in PT
increased fall risk

561 Pharm (21 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions