Analgesic Drugs Flashcards
allodynia
pain from a stimulus that does not normally provoke pain
hyperalgesia
increased pain from stimulus that normally provokes pain
hypoalgesia
diminished pain in response to a normally painful stimulus
neuralgia
pain in nerve distribution
neuritis
inflammation of nerve
nociceptive pain
pain arises from actual or threatened damage or non neural tissue due to activation of nociceptors
neuropathic pain
pain caused by a lesion or damage or disease of the neurons/somatosensory nervous system
adjuvant pain medication
meds not typically used for pain but helpful in its management
eg antidepressants
pain meds acting on perception
opioids, tcas, ssri, snri, alpha 2 agonists
pain meds acting on modulation
tcas, ssris, snris
pain meds acting on signal transission
las, opioids, alpha 2 agonists
pain meds acting on local signal transduction
las, capsacin, anticonvulsants, nsaids, asa, acetaminophen, nitrate
endogenous opioids
peptides
endorphins: from POMC, mu agonist with delta action
enkephalins: from proenkephalin; Met-ENK and leu-ENK