medical marijuana

Question 1

cannabis classification: legal

Answer 1

schedule 1

Question 2

psychoactive cannabinoid

Answer 2

delta 9 THC

Question 3

cannabinoid lowering inflammation and pain

Answer 3

cannabidiol/CBD

Question 4

uses of medical marijuana

Answer 4

pain
spasticity
depression
anxiety
glaucoma
insomnia
psychosis
seizures

Question 5

side effects of marijuana

Answer 5

short term memory loss
dry mouth
impaired motor skills
red eyes
anxiety

Question 6

safety concerns with marijuana

Answer 6

not used in pregnant women
abuse
drug interactions
interferes w brain development in adolescents

Question 7

CBD uses

Answer 7

anxiety
chronic pain
epilepsy (epidiolex)
sleep disorders

Question 8

side effects of CBD

Answer 8

fatigue
diarrhea
changes in appetite
drug interactions

Question 9

cannabinoid MOA

Answer 9

1. presynaptic neuron releases NT to activate post synaptic neuron
2. activated post synaptic neuron releaeses endocannabinoids
3. endogenous CB1 ligand binds presynaptic receptor
4. CB1 receptor activates G protein inhibiting NT release
5. nabilone/synthetic cannabinoids activate CB1 receptors directly to mimic endocannabinoids

Question 10

FDA approved cannabinoids

Answer 10

dronabinol: stimulate appetite in pts w AIDS, cancer by mitigating nausea
nabilone: nausea/vomiting from chemo
cannabidiol: seizures from rare forms of epilepsy

Question 11

PT considerations for CBD and medical marijuana

Answer 11

pain management, avoid overexertion
cog and motor function reduced when active
lethargy and relaxation could decrease motivation
be aware of state’s regulation on marijuana
pt education