Intro to Analgesics Flashcards
A beta fibers transmit…
fiber type?
mechanical stimulus, non noxious
myelinated, large - fast
A delta fibers transmit…
fiber type?
noxious mechanical
myelinated, large - fast
C fibers transmit…
fiber type?
noxious heat and chemical
unmyelinated, smaller - slower
pain perception and how analgesics fx
pain not felt until reaching brain
can either stop the signals from reaching the brain or increase pain modulation/pain blocking signals from the brain
spinothalamic tract
discriminative/localization of pain
projects to thalamus and cortex to generate pain perception for a specific body region
spinobulbar tract
affective/intensity of pain
projects to amygdala/hypothalamus
recruits descending pain control
promote or inhibit nocicpetion through spinal cord
gate control theory
non painful input can close the gate to painful input since they travel along the same pathway
types of chronic pain
nociceptive - inflammatory
neuropathic - central or peripheral nervous system
mixed - LBP, cancer, fibromyalgia
visceral - organs
differences between acute and chronic pain
cause: acute known/chronic unknown
duration: short/persisting
treatment: resolve cause/address pain disorder or control pain
allodynia
pain from non painful stimulus like thermal or mechanical
hyperalgesia
exaggerated response to a painful stimulus
hyperesthesia
exaggerated response to touch
hyperpathy
persistent pain even after the cause of pain has been removed
categories of analgesics
pain relief
opioid:semisynthetic/synthetic for relieving mod to severe pain
nonopioid: ibuprofen, acetaminophen
Which analgesics act on the brain
perception and pain modulation
opioids
NSAIDS
ketamine
TCAs
gabapentinoids
benzodiazepines
