Sedation Flashcards
what is the medicine administered in IV sedation
midazolam
what is the medicine administered in inhalation sedation
nitrous oxide
what is the definition of sedation
technique in which the use of a drug produces a state of depression in the CNS
name three complications of cannulation
venospasm
extravascular injection
haematoma
fainting
what is venospasm and what is it associated with
veins collapsing at attempted venepuncture
caused by poorly visible veins
what is extravascular injection and what problems can this cause
active drug is put into interstitial space and not a vein
causes delayed absorption of drug
what is a haematoma
extravasation of blood into soft tissue due to damage of vein walls
name five complications of drug administration
hyperresponders
hyporesponders
paradoxical reactions
oversedation
allergic reactions
what is the average dose of midazolam given
5-6mg
why may patients be hypo-responders to sedation
cross tolerance from taking recreational drugs
idiopathic
what is the maximum threshold of midazolam you should give before calling it a day
10mg in general practice
15mg in hospital setting
side effects of midazolam are increased in patients on what
opioids
what are paradoxical reactions
patients don’t sedate - they may appear hyper
name three effects that occur with oversedation
loss of responsiveness
respiratory depression
loss of ability to maintain airway
what is the reversal drug for midazolam
flumazenil 200mg
when an allergic reaction to midazolam occurs what should you do
do NOT give flumazenil (same family of drug)
what is the elimination half life of midazolam
1-2 hours - so the drug can be in the system for 12 hours
must have someone chaperone them