Second year exams topics Flashcards

1
Q

build up of what in porphyria cutanae tarda

A

urophorphinogen

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2
Q

what would be the cause of a child crying when in direct sunlight

A

erythropoietic protopophyria

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3
Q

first line treatment for acne rosacea

A

topical metreo

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4
Q

first line treatment for acne vulgaris

A

benzyl benzoate or topical clinda

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5
Q

what is epidermolysis bullosa

A

breakdown of anchoring between epidermis and dermis

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6
Q

which insulin do u give once a day

A

basal - e.g. lantus

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7
Q

which diabetic drug is weight neutral

A

DPP4 inhibit - sitagliptin

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8
Q

strawberry milkshake coloured blood

A

hyperlipidaemia

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9
Q

pagets biochem

A

normal calcium normal phos

high alk phos

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10
Q

what hormone do u test for preg

A

hcg

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11
Q

what hormone peaks before ovulation

A

LH 12 hours before

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12
Q

what hormone do u test for fertility

A

progesterone

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13
Q

what is pagets
symp
treatment
cx

A

osteoclastic reabsorption followed by increased osteoblastic activity

bone pain - femur, spine, pelvis

bisphosphonates - risedronate

deafness, cardiac failure, fractures, skull thickening

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14
Q
osteomalacia is what
why
causes
symp
rx
A

rickets in children
low calcium low phos high alk phos
abnormal softening of bone due to deficient mineralisation of osteoid (immature) bone

vit D defic

bone pain, tenderness, fractures, waddling gait

vit D therapy with calcium and phosphate supplements

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15
Q

which drug causes reactivation of latent TB

A

etenercapts, inflixumab

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16
Q

which drug causes interstitial pneumonitis

A

methotrexate

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17
Q

which rheumatoid drug causes black tarry stools

A

NSAIDs

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18
Q

tingling in ring and pinky finger

A

cubital tunnel syndrome

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19
Q

which rheumatoid drug is nephrotoxic

A

gold, penicillamine

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20
Q

visual loss, mouth ulcers, genital ulcers

A

bechets syndrome

CSR and ESR raised

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21
Q

inflam condiiton assoc with IBD

A

enteropathic arthritis

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22
Q

placental artery

placental vein

A

deoxygynated

oxygenated

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23
Q

compression of facial nerve in facial canal

A

bells palsy

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24
Q

ramsay hunt syndrome
symp
rx

A

reactivation of varicella zoster in geniculate ganglion of CN7
auricular pain, facial palsy, vesicular rash around ear, vertigo and tinnitus

oral aciclovir and corticosteroids

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25
central scrotoma
absence of central vision | dry ARMD, optic neuritis
26
third nerve palsy
down and out fixed dilated pupil proptosis ptosis
27
fourth nerve palsy
eyes look upwards vertical diplopia cannot look down and in head tilted
28
sixth nerve palsy
horizontal diplopia eyes medially deviated and cannot move laterally form midline convergent squint - start in
29
treatment of bph | dx
first line alpha blocker - tamsulosin second line 5 alpha reductase - finestride TRUS with biopsy
30
first line ix in hydrocele
doppler USS with colour
31
what do you give for proteinuria and hypertension
ACIE
32
stage 3 CKD
30-60
33
IgA nephropathy
increased IgA lserum levels | assoc with HSP
34
pANCA
churg strauss | EGPA
35
cANCA PR3
EGP | wegners
36
which Ig is found in mucosa
IgA
37
what produces endotoxin | exotoxin
gram negative | gram pos
38
CF gene is what | mum dad are unaffected but daughter is affected what are the chances that the other unaffected daughter is a carrier
autosomal recessive 2/3
39
side effects ACEI | what is it contraindicated in
dry cough | renal artery stenosis
40
different organisms in gastroenteritis
e.coli | campylobacter
41
side effect of spironolctone
gynacamastea
42
what type of mouth disease do people with crohns have
stomatitis gangrenosum
43
chlamydia pstacci
birds
44
coexiella burnetti
sheep/farm
45
legionella
water foreign holiday urinary antigen
46
abnormal field visions sweaty and hot large jaw fleshy fingers
acromegaly
47
SIADH
sodium dilution
48
spermatogenesis where | which cells secrete what acted on by ?
seminiferous tubules | leydig cells secrete testosteonr (acted on by LH)
49
what cells enhance spermatogenesis acted on by what
sertoli cells | FSH
50
osteomalacia oseoperosis pagets
vit D, soft bones decreased bone mass abnormal bone formation and resorption
51
most common bone tumour
osteosarcoma
52
painful arch
supra
53
eversion of foot?
deltoid ligament | lateral compartment of the leg
54
inversion of foot
anterior and posterior compartments of the leg
55
nerve supply to trapezius | what movement
CNXI spinal accessory | shrugs shoulder
56
what causes amyloidosis of the kidneys
rheumatoid arthritis
57
treatment f tetanus
penicillin metro surgery
58
femurs splint
thomas splint
59
gallazzi
old ladies and humerus fracturesa
60
why do greenstick fractures occur in children
bones are soft
61
can membrane nephropathies cause malignancy
yes
62
official name of viagra | type of drug
sildenafil | phosphodiesterase inhibitor
63
hydrocele
transluminates
64
palpate above a testicular lump
not a hernia
65
bulbourethral gland
lies posterior to membranous urethra
66
splitting of which structure would prevent seminal fluid from entering the urethra
bladder sphincter
67
what covers the testis
tunica vaginlais
68
peritoneal dialysis causes what
weight gain
69
davenport diagram where is resp acidosis
top left
70
right gonadal vein come off which structure
IVC
71
left gonadal vein comes off which structure
left renal vein
72
difference test done between scleritis and epi
epi - phenlyphrine test | redness will blanch
73
grey baby syndrome
chloramphenicol
74
seeing scratches on the eyes
fluorescin
75
test for hypersensitive 1 and 4
1 IgE levels | 4 patch tests
76
measure dysplastic naevi by what
breslow thickness
77
eczema | psoriasis
flexors | extensors
78
phemphigious | phemphigoid
above DEJ membrane and acantholysis occurs | between dermis and epidermis
79
colles fracture
fall onto outstretched hand | dinner fork
80
scaphoid imagine
2 obliques 1 aP 1 lateral
81
NAI
can't age a bruise
82
what can pagets predispose to
osteosarcoma
83
risk factors for skin cancer
childhood sunburns, occupation related to high sun exposure, fair skin
84
final acne treatment is what
carcinogenic
85
mild acne is what | treatment
blackhead/white heads mostly ``` prescribe one of topical retinoid. benzyle benzoate if neither work then azelic acid COC in women follow up in 6-8 weeks ```
86
ramsay hunt
shingles in the ear | old people
87
molloscum contagiosum
kids get them mostly | can be sexually transmitted
88
tuning fork for diabetic foot
128
89
treat endometrial polyps
myomectomy
90
when should amox not be given
glandular
91
guttate psoriasis
small discoids | mostly viral
92
ring worm looks like what
target
93
monomorphic punched out lesions in eczema
dermatitis herpeticum caused by HSV treat w aciclovir
94
baby finds it difficult to breath especially when feeding
choanal atresia
95
side effects of alpha blockers (tamsulisin)
postural hypotension and dizziness
96
5 alpha blockers side effects
erectile dysfunction decreased libido gynacamastia
97
pityriasis rosacea
herald patch
98
treatment of impertigo
topical fusidic cream | oral flucox