Derm 2

Question 1

chicken pox vaccines in who

Answer 1

susceptible health care workers

VZ Immunglobulin to susceptible women as neonatal VZV is secondary to chicken pox in mothers during pregnancy

Question 2

shingles vaccine to who

Answer 2

same chicken pox vaccine in high titre to >70s to reduce the impact of shingles

Question 3

lyme disease treatment

Answer 3

amox (doxy)

Question 4

orf is what

treatment

Answer 4

soft fleshy nodule on hands of farmers

self limiting

Question 5

mallosum contagious in who
what
transmission
treatment

Answer 5

children
fresh firm umbilicated nodule 1-2mm diameter
can be sexually transmitted
self limiting

Question 6

erythema infectosium is caused by what
what is it
complications

Answer 6

paravirus B19
slapped cheek syndrome
complications of paravirus B19 - spontaneous abortion, chronic anaemia in immunosuppressed, arthritis in wrists as rash fades (in adults)

Question 7

primary gingovitis in who

what is it

Answer 7

pre school children

blisteres, rash at vermillion border, extensive ulceration

Question 8

herpangioma caused by what
what is it
ix
rx

Answer 8

enterovirus
blistering rash at back of mouth
swab. stool sample
self limiting

Question 9

necrotising fascitis is what
symp
types
treatment

Answer 9

bacterial spread under the surface of the skin
painful and rapid
type 1 - mixed anaerobes and coliforms usually post abd surgery
type 2 - group A strep
urgent debridement and ABs depending on organism

Question 10

scabies is what
norwegian scabies
treatment

Answer 10

intensely itchy rash affecting finger webs, wrists, genital area
chronic crusted scabies - highly infectious - elderly or immunocompromised 
benzyle benzoate (not in children), malathion lotion

Question 11

ringworm treatment for scalp
small areas of skin
topical nail paint

Answer 11

terbinefine PO, tracomazole PO
co triazole cream
topical nail pain - omeralfine

Question 12

candida symp
candida intertrigo
treatment

Answer 12

red moist skin with ragged peeling edge and pustules and papules at margin

infection in skin folds where area is moist and warm

topical clotrimazole. topical terbinafine
if treatment not working, patient immunocompromised or extensive disease - PO flucomazole

Question 13

Acne treatment

Answer 13

benzene benzoate 
topical ABs
retinoids 
systemic - ABs
isotrtinoid

Question 14

psoriasis phenomenon

treatment

Answer 14

koebers - new lesions arise at site of trauma
topical vit D analogues - calcipricol
retinoids, coal tar, biologics

Question 15

rosacea exacerbated by what
treatment
assoc w what

Answer 15

sudden change in temp, alcohol, spicy food
topical methotrexate, oral tetracycline
dedox mite

Question 16

bullous pemphigoid split
ABs
ix
treatment

Answer 16

deep split through the DEJ
hemidesmasome ABs
nikosky -ve
tetra, nicotinamide, azithro

Question 17

bullous phemphigous split
ABs
ix
treatment

Answer 17

split superficial - intraepidermal 
ABs against desmoglen 3
nicoski positive 
chicken wire on skin biopsy with immunofluerence 
topical/systemic steroids

Question 18

derm herpetiforms symp

assoc with

Answer 18

itch symmetrical on elbows/knees/bum
papillary dermal abscesses
coeliac disease

Question 19

seborrhoic keratosis common in who
signs
what is it

Answer 19

ageing skin
face/trunk stuck on appearance brown/black greasy
benign proliferation of keratinocytes

Question 20

normal abnormal ABPI

Answer 20

0.8-1.3 normal
<0.8 vascular disease
>1.5 calcification

Question 21

venous leg ulcer

Answer 21

shallow round the edge like a beach

around malleolus

Question 22

arterial leg ulcers

Answer 22

sharp cliff like edges
punched out
pressure site - feet

Question 23

precursors of SCC

Answer 23

bowens - F>M lower leg. scaly patch/plaque
actinic keratosis - scalp/face/hands
viral - HPV (?)

Question 24

SCC looks like

risk

Answer 24

hyperkeratosis crusted lump/ulcer
grow fast 
may be painful/ bleed
ear, lip, scalp 
risk of mets 5%

Question 25

BCC in who where

what does it look like

Answer 25

middle aged. sub exposed sites 
slow growing lump or non healing ulcer 
pearly, translucent, visible arborising vessels 
central ulceration - rodent ulcer
can present as superficial plaque

Question 26

porphyria ix

Answer 26

woods lamp

Question 27

contact allergic derm is what

ix

Answer 27

specific. type 4 hs

patch testing - leave on for 48 hours, check after 96 hours

Question 28

irritant contact derm is what

Answer 28

non specific

Question 29

SA infection of eczema

Answer 29

crusting. cycle of scratch of itch

Question 30

HIV infection of eczema

Answer 30

eczema herpeticulum

monomorphic punched out lesions

Question 31

adhesin

Answer 31

binding of organism to host cell

Question 32

invasion

Answer 32

invade host cell and tissue

Question 33

impendin

Answer 33

avoid host cell mechanisms

Question 34

aggressin

Answer 34

damage to host cell directly

Question 35

modulin

Answer 35

damage to host cell indirectly