Derm 2 Flashcards
chicken pox vaccines in who
susceptible health care workers
VZ Immunglobulin to susceptible women as neonatal VZV is secondary to chicken pox in mothers during pregnancy
shingles vaccine to who
same chicken pox vaccine in high titre to >70s to reduce the impact of shingles
lyme disease treatment
amox (doxy)
orf is what
treatment
soft fleshy nodule on hands of farmers
self limiting
mallosum contagious in who
what
transmission
treatment
children
fresh firm umbilicated nodule 1-2mm diameter
can be sexually transmitted
self limiting
erythema infectosium is caused by what
what is it
complications
paravirus B19
slapped cheek syndrome
complications of paravirus B19 - spontaneous abortion, chronic anaemia in immunosuppressed, arthritis in wrists as rash fades (in adults)
primary gingovitis in who
what is it
pre school children
blisteres, rash at vermillion border, extensive ulceration
herpangioma caused by what
what is it
ix
rx
enterovirus
blistering rash at back of mouth
swab. stool sample
self limiting
necrotising fascitis is what
symp
types
treatment
bacterial spread under the surface of the skin
painful and rapid
type 1 - mixed anaerobes and coliforms usually post abd surgery
type 2 - group A strep
urgent debridement and ABs depending on organism
scabies is what
norwegian scabies
treatment
intensely itchy rash affecting finger webs, wrists, genital area chronic crusted scabies - highly infectious - elderly or immunocompromised benzyle benzoate (not in children), malathion lotion
ringworm treatment for scalp
small areas of skin
topical nail paint
terbinefine PO, tracomazole PO
co triazole cream
topical nail pain - omeralfine
candida symp
candida intertrigo
treatment
red moist skin with ragged peeling edge and pustules and papules at margin
infection in skin folds where area is moist and warm
topical clotrimazole. topical terbinafine
if treatment not working, patient immunocompromised or extensive disease - PO flucomazole
Acne treatment
benzene benzoate topical ABs retinoids systemic - ABs isotrtinoid
psoriasis phenomenon
treatment
koebers - new lesions arise at site of trauma
topical vit D analogues - calcipricol
retinoids, coal tar, biologics
rosacea exacerbated by what
treatment
assoc w what
sudden change in temp, alcohol, spicy food
topical methotrexate, oral tetracycline
dedox mite
bullous pemphigoid split
ABs
ix
treatment
deep split through the DEJ
hemidesmasome ABs
nikosky -ve
tetra, nicotinamide, azithro
bullous phemphigous split
ABs
ix
treatment
split superficial - intraepidermal ABs against desmoglen 3 nicoski positive chicken wire on skin biopsy with immunofluerence topical/systemic steroids
derm herpetiforms symp
assoc with
itch symmetrical on elbows/knees/bum
papillary dermal abscesses
coeliac disease
seborrhoic keratosis common in who
signs
what is it
ageing skin
face/trunk stuck on appearance brown/black greasy
benign proliferation of keratinocytes
normal abnormal ABPI
0.8-1.3 normal
<0.8 vascular disease
>1.5 calcification
venous leg ulcer
shallow round the edge like a beach
around malleolus
arterial leg ulcers
sharp cliff like edges
punched out
pressure site - feet
precursors of SCC
bowens - F>M lower leg. scaly patch/plaque
actinic keratosis - scalp/face/hands
viral - HPV (?)
SCC looks like
risk
hyperkeratosis crusted lump/ulcer grow fast may be painful/ bleed ear, lip, scalp risk of mets 5%
BCC in who where
what does it look like
middle aged. sub exposed sites slow growing lump or non healing ulcer pearly, translucent, visible arborising vessels central ulceration - rodent ulcer can present as superficial plaque
porphyria ix
woods lamp
contact allergic derm is what
ix
specific. type 4 hs
patch testing - leave on for 48 hours, check after 96 hours
irritant contact derm is what
non specific
SA infection of eczema
crusting. cycle of scratch of itch
HIV infection of eczema
eczema herpeticulum
monomorphic punched out lesions
adhesin
binding of organism to host cell
invasion
invade host cell and tissue
impendin
avoid host cell mechanisms
aggressin
damage to host cell directly
modulin
damage to host cell indirectly
