Derm skin stuffs

Question 1

semisolid

hair bearing areas, scalp

Answer 1

gels

Question 2

semisolid emulsion of oil in water, non greasy, conservative and preservative, high h2o content

Answer 2

creams

Question 3

semi solid
finely powdered material 
bandages
stiff, greasy, difficult to apply
protective, occlusive

Answer 3

pastes

Question 4

semisolid grease

greasy, restrict transepidermal water loss, occlusive, no preservative

Answer 4

ointment

Question 5

liquid formation, treat scalp hear bearing areas, can sting if contains alcohol, suspension or solution of medicine in water/alcohol

Answer 5

lotion

Question 6

stratified cellular epithelium

connective tissue

Answer 6

epidermis

dermis

Question 7

where do keratinocytes migrate from and how long does it take them to reach the top

Answer 7

BM

28 days

Question 8

what does the granular layer consist of
type of bodies?
3 points

Answer 8

2-3 layers of flatter cells
large certain granules, odland bodies (lamellar bodies)
high lipid content, origin of cornfield envelope, cell nuclei lost

Question 9

what kind of cells does the prickle cell layer have

Answer 9

larger polyhedral cells

Question 10

how thick is the basal cell layer and 1 point

Answer 10

1 cell thick - small cuboidal

highly metabolic

Question 11

give the break down of cells in the epidermis

Answer 11

95% keratins 5% langerhans, melanocytes, merkel cells

Question 12

where do langerhan cells come from
where are they
where else are they found
1 point

Answer 12

mesenchymal origin - bone marrow
supra basal - prickle cell layer
dermis and LN
racket organelle (birbceck granules)

Question 13

where do melanocytes come from
where are they
what do they do (3)

Answer 13

migrate from neural crest to epidermis in first 3 months
basal and supra basal
tyrosine - melanin, absorb light and transfer it to keratinocytes, form protective cap over nuclear DNA in basal cells

Question 14

vitiligo
albinism
nelsons

Answer 14

AI loss of melanocytes
genetic partial loss of pigment production
increased hormone production

Question 15

where are merkel cells

what are they

Answer 15

basal - between keratinocytes and nerve fibres

mechanoreceptors

Question 16

anagen
catogen
telogen

Answer 16

growing
involuting
resting

Question 17

epidermolysis bullosa caused by what

Answer 17

inherited skin fragility due to mutation in a protein in DEJ

Question 18

phemphigous, phemphogoid, derm herpetiformis

Answer 18

acquired autoAB to protein in DEJ

Question 19

cells of the dermis and what they do

Answer 19

fibroblasts - collagen 
macrophages
lymphocytes
langerhan cells
mas cells

Question 20

the types of fibres in the dermis

Answer 20

elastina and collagen

Question 21

blood vessels in the dermis - 1 point

a cx of them

Answer 21

supply greater than need as the skin is a thermoregulatory

angioma - overgrowth of blood vessels

Question 22

give two types of somatic sensory corpuscles

cx of nerve fibres

Answer 22

pacinian - pressure, mesissners - vibration

neurofibromas - overgrowth of nerve endings

Question 23

function of the sebaceous gland

Answer 23

control moisture loss and protection from bacterial and fungal infection

Question 24

what are apocrine glands
where are they
what are the dependent on 
when do they work
what do they produce

Answer 24

scent glands
w the pilosebaceous unit. axilla and perineum
androgen
when hit puberty
fluid-> odour after bacterial decomposition

Question 25

what do eccrine glands produce
where are they
function

Answer 25

sweat when too hot
palms, soles, axilla - but everywhere
cool by evaporation, moisten palms/soles to drip