Schizophrenia & Other Psychotic Disorders

Question 1

psychosis

Answer 1

formal thought disorder, delusion, hallucination

Question 2

formal thought disorder

Answer 2

loosening of associations, “word salad”; blocking (subjective); neologism

Question 3

delusion

Answer 3

grandiose, paranoid, somatic, religious, reference

Question 4

brief psychotic disorder

Answer 4

formal thought disorder, delusion, hallucination <1m, can occur w/ or w/o stressor

Question 5

delusional disorder

Answer 5

1+ delusion (+/- hallucinations) for >1 month, often chronic; no formal thought disorder, no significant mood symptoms
(themes: erotomanic, grandiose, jealous, persecutory)

Question 6

schizophrenia

Answer 6

formal thought disorder/delusion/hallucination + 1 symptom of grossly disorganized behavior or catatonia OR 1 negative symptom (active phase, 1m); COGNITIVE DYSFUNCTION, prodromal and residual symptoms (w/ active phase, >6m)

Question 7

grossly disordered behavior

Answer 7

stupor, catalepsy, waxy flexibility, mutism

Question 8

negative symptoms

Answer 8

avolition, alogia, asocial, anhedonia, flat affect

Question 9

schizophreniform

Answer 9

schizophrenia, <1m duration; 1/3 will recover fully; 2/3 will have schizophrenia/other psychotic disorder

Question 10

epidemiology

Answer 10

onset 20s, 1:1 M:F ratio, schizophrenia: 1% worldwide

Question 11

etiology of schizophrenia

Answer 11

1) neurodevelopmental model- early defect manifests later in evolved function later in life
2) neurodegenerative model- degeneration over time
3) stress- diathesis model- 50% risk with identical twin, stress includes famine during pregnancy, season of birth, birth location

Question 12

treatment

Answer 12

antipsychotic medications, cognitive behavioral therapy, (employment, family intervention, community treatment)