Schizophrenia Flashcards
What are some positive symptoms?
Hallucinations
Delusions
Agitation
Disorganised thinking
What are some negative symptoms?
Introversion
Apathy
Low self-esteem
Personal neglect
What are some cognitive symptoms?
Poor memory
Attention deficit
Executive dysfunction
What two (out of 5) things must schizophrenic patients have experienced?
Delusions Hallucinations Disorganised speech Disorganised or catatonic behaviour Negative symptoms
How long must schizophrenic signs last for?
6 months (one month of active symptoms)
What genes are associated with schizophrenia?
BDNF COMT DAOA Neuregulin 1 Dysbindin DISC1
What are the different classes of schizophrenia?
Paranoid Disorganised Catatonic Undifferentiated Residual
What is schizophrenia associated with?
decreased synaptic spines
What is schizophrenia associated with in the cortex?
decreased dendritic complexity
What happens with regard to the mesolimbic pathway in schizophrenia?
hyperactivity
What does schizophrenia cause hypoactivity in?
mesocortical pathway
What D1 receptors are known for treatment?
D1 and D5
What D2 receptors are known for treatment?
D2, 3 and 4
Give examples of schizophrenic treatment
Typical antipsychotics
Atypical antipsychotics
How do you test for Frontal cortical dysfunction?
Wisconsin Card Sorting Test