Cerebellum Flashcards

1
Q

Where is the cerebellum found?

A

Posterior cranial fossa

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2
Q

What is the midline of the cerebellum called?

A

Vermis

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3
Q

What is the vermis divided into?

A

Anterior and posterior obe

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4
Q

Which lobe of the vermis is larger?

A

Posterior

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5
Q

Is the posterior lobe superior or inferior to the anterior lobe?

A

More inferior

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6
Q

What is the sulcus called between anterior and posterior lobe?

A

Primary fissure

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7
Q

What is the 3rd, smaller lobe called in the cerebellum?

A

Flocculonodular node

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8
Q

What is the flocculonodular node contain and responsible for?

A

Flocculus

Vestibulo-ocular reflex

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9
Q

What are inferior on the cerebellum?

A

cerebellar tonsils

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10
Q

If ICP raises, what happens to the cerebellar tonsils?

A

They herniate trhrough foramen magnum

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11
Q

What happens if cerebellum tonsils hernaite?

A

Compress upper spinal cord blood vessels and tracts

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12
Q

What is separate to the vermis?

A

Nodulus lobe

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13
Q

What does nodulus lobe do?

A

Helps form part of 4th ventricle

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14
Q

What mainly supples blood to cerebellum?

A

Posterior inferior and superior cerebellar arteries

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15
Q

What else supplies blood to cerebellum?

A

Branches of basilar artery

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16
Q

Which is the most common site of an infarct in posterior circulation

A

PICA

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17
Q

How many layers are there to the cerebellum?

A

3 layers

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18
Q

Describe the outer layer of the cerebellum

A

Pale with mostly axons and only a few cells

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19
Q

What does the middle layer have?

A

purkinje cells

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20
Q

What does the inner layer have

A

Granular layer with cell bodies

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21
Q

Where do all inputs and outputs to the cerebellum go through?

A

Cerebellar peduncles

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22
Q

What does the superior peduncle contain?

A

output fibres only

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23
Q

What does the middle peduncle contain?

A

Input fibres from contralateral cortex and cranial nerves via the pons

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24
Q

What does the inferior peduncle contain?

A

Input fibres from spinal cord via the dorsal and ventral spinocerebellar tracts

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25
Where are all inputs and outputs routed through to get to the rest of the brain?
Deep cerebellar nuclei which lies in white matter
26
From medial to lateral, what are the deep cerebellar nuclei?
Fastigial, Globose, Emboliform and Dentate (FGED)
27
Which nuclei does the vermis connect to?
Fastigial
28
Which nuclei does the anterior lobe of the cerebellum connect to?
Interposed nuclei (globose + emboliform)
29
The hemispheres connect to which nuclei?
Dentate nuclei
30
Where does spinocerebellar tract originate?
Spinal cord
31
Where does spinocerebellar tract terminate?
Ipsilateral cerebellum
32
What does the spinocerebellar tract convey information about?
Length and tension of muscle fibres
33
What does spinocerebellar tract control?
Unconscious proprioceptive sensation
34
Is the dorsal tract ipsilateral or contralateral?
Wholly ipsilateral
35
Where does dorsal tract pass up?
Passes up brain stem
36
How does dorsal tract enter cerebellum?
Via inferior cerebellar peduncle
37
What does dorsal tract do?
Carry information from proprioceptors
38
Is ventral tract contralateral or ipsilateral?
Contralateral but recrosses brainstem to become ipsilateral
39
What does ventral tract do?
Carries information about state of reflexes and interneurones in the spinal cord
40
What are the 3 function zones in the cerebellum?
Vestibulocerebellum Spinocerebellum Cerebrocerebellum
41
What is the function of the cerebellum?
Help motor cortex produce accurate and smooth movements
42
How does cerebellum do its function?
Modulating and refining motor cortex commands using feedback from proprioceptors and other sensory organs
43
What does cerebellar damage cause?
Overall clumsiness abnormal fatigue Instability of movement Extraocular eye muscles are affected
44
What does cerebellar white matter have the property of?
neuronal plasticity
45
Damage to what causes persistance of disability
deep nuclei
46
What does the vestibulocerebellum operate via
flocculonodular lobe
47
What is connected to the vestibulocerebellum?
Vestibular nuclei
48
What does vestibullocerebellum do?
coordinates head and eye movements to ensure gaze stability
49
What does vestibulospinal tract do?
controls balance of head on body
50
What does lateral vestibular tract do?
Controls balance of whole body
51
Where is information sent from to the vestibular nuclei?
Medulla/ pons
52
Motor commands to neck and eye muscles are sent via what?
Medial longitudinal fasciculus | Medial vestibulospinal tract
53
Motor commands to the legs go via?
lateral vestibulospinal tract
54
Motor programs for tasks are stored where?
cortex of the flocculo-nodular lobe
55
What is the spinocerebellum comprised of?
anterior lobe and vermis
56
What does verims connects to
fastigial nucleus
57
What is the anterior lobe connected to?
interposed nuclei
58
What does the spinocerebellum control?
locomotion and limb coordination
59
What does the spinocerebellum send motor commands down?
lateral vestibulospinal | reticulospinal tracts
60
What is the cerebrocerebellum comprised of?
posterior lobe (cerebral hemispheres)
61
What is the cerebral hemispheres connected to?
dentate nucleus
62
What does the cerebrocerebellum do?
coordinates movement initiated by motor cortex | (speech, voluntary movements of hands/arms and hand eye coordination
63
What are the 3 major cerebellar syndromes?
Flocculonodular Anterior lobe Neocerebellar
64
What characterises flocculonodular syndrome?
Poor balance and disordered eye movements
65
What is a common cause of flocculonodular syndrome?
Medulloblastoma
66
Where does a medulloblastoma usually ordinate?
Wall of 4th ventricle
67
What is medulloblastoma a form of?
cranial primitive neuroectodermal tumour (PNET)
68
What is the anterior lobe correlated with?
Damage to spinocerebellum
69
What is anterior lobe syndrome characterised by?
Incoordination of the limbs
70
Where is the anterior lobe syndrome usually seen in?
Alcoholics due to lack of B vitamins
71
What is the neocerebellum?
Cerebella hemispheres + dentate nuclei
72
What is neocerebellar syndrome symptoms?
Loss of hand-eye coordination | Loss of good speech due to loss of coordination of muscles involved
73
What is dysmetria?
Inaccurate reaching with an intention tremour
74
Causes of neocerebellar syndrome?
Loss of cognitive eye movement Stroke Tumour Trauma
75
What does cerebellar stroke usually involve?
Whole cerebellar cortex on one side
76
What are signs of cerebellar stroke?
``` Headache Nausea/vomiting Eye changes (one eye + vertigo) Dysarthria Dysphagia Ataxia Arm weakness + coordination ```
77
What mimics cerebellar stroke
Alcohol intoxications
78
Why does alcohol mimic cerebellar stroke?
Cerebellum has many GABA-ergic interneurones sensitive to alcohol