RSL - Derm Flashcards
Obstructive and inflammatory disease of pilosebaceous unit
Acne
Intense pruritis triggered by environment and associated with asthma
Atopic dermatitis
Lichenification of flexor regions
Atopic dermatitis
Type 1 IgE mediated hypersensitivity
Atopic dermatitis and urticaria
Type IV hypersensitivity at site of touching
Allergic contact dermatitis
Papular intradermal nevi
Melanocytic nevus
Acanthosis with parakeratotic scaling.
Psoriasis
Increased stratum spinosum, decreased stratum granulosum
psoriasis
Auspitz sign
pinpoint bleeding spots from exposure of dermal papilae when psoriasis scales scraped off
Nail pitting and arthritis
psoriasis
Psoriasis treatment
UVA light with psoralen
elongated rete ridges and neutrophils in stratum corneum
Psoriasis
Inflammatory facial skin disorder with erythemaous papules and pustules but no comedones
Rosacea
Facial flushing in response to external stimuli
Rosacea
Chronic inflammatory changes may result in rhinophyma
Rosacea (bulbous deformation of the nose)
Keratin filled horn cysts
Seborrheic keratosis
Leser-trélat sign
sudden appearance of multiple seborrheic keratosis indicated underlying malignancy
Soft, tan colored, cauliflower like papules
Verrucae
Epidermal hyperplasia, hyperkeratosis, koilocytosis
Verrucae (HPV)
Pruitic wheals
Urticaria
Superficial dermal edema and lymphatic channel dilation
Urticaria
Cellulitis vs erysipelas
Cellulitis = deeper dermis and subcutaneous fat.
Erysipelas = upper dermis and superficial lymphatics,
- Distinctive anatomic features than cellulitis; erysipelas lesions are raised above the level of surrounding skin, and there is a clear line of demarcation between involved and uninvolved tissue
Target lesions with multiple rings and dusky center showing epithelial disruption
erythema multiforme
Mild version of SJS
Erythema multiforme
Eitiology of Erythema Multiforme
Infections: (m. pneumoniae, HSV), drugs: (sulfa, beta-lactams, phenytoin), cancers, autoimmune disease.
Fever, bullae, necrosis, sloughing of skin
SJS
Symmetric, hyperpigmented thickening of skin
Acanthosis nigricans
Sand paper texture, hyperkeratosis, parakeratosis, atypoical keratinocytes
Actinic keratosis
Painful, inflammatory, lesions of subcutaneous fat, usually on shins
Erythema nodosum
Eitiology of erythema nodosum
Idiopathic, sarcoidosis, coccidiodomycosis, histoplasmosis, TB, streptococcal infections, leprosy, crohns
Itchy, flat, papules and plaques, purplish
Lichen planus
Wickham striae
Lichen planus (reticular white lines)
Sawtooth infiltrate of lymphocytes at dermal epidermal junction
Lichen planus
CD 8+ mediated autoimune reaction to Basal cells
Lichen planus
Associated with Hep C
Lichen plaus
Herald patch
Pitryasis rosea
skin markings followed by scaly erythematous plaques in tree distribution
Pitryasis rosea
Limited scleroderma
CREST: Calcinosis, Raynaud, esophageal dysmotility, and telangiectasia
Diffuse scleroderma
Skin involvement, Anti-Scl-70 Ab.
Scleroderma; triad
Autimmunity, non-inflammatory vasculopathy, collagen deposition with fibrosis
Scleroderma; common sites
Skin; puffy taut skin without wrinkles. Sclerosis of renal, pulmonary (MCC of death), cardiovascular, GI systems
Melasma
Hyperpigmentation associated with pregnancy
