RSL - Behavioural Science Flashcards
Cross sectional study: Asks?
What is happening (72 % of the people with COPD smoke)
Cross sectional study: Measures
Disease prevelance
Case-control study: Asks?
What happened (People with COPD had a higher odds of history of smoking)
Case-control study: Measures?
Odds ratio
Cohort study: Asks?
What will happen (smokers had higher risk of developing COPD)
Cohort study: Measures?
Relative risk
Prevelance and PPV/NPV
prevalence:PPV
Prevalence: 1/NPV
Odds ratio
OR = AD/BC
Relative risk
RR = a/(a+b) ÷ c/(c+d)
[risk of getting disease in exposed / risk of getting disease in non-exposed]
Prevalence, OR, RR
If prevalence is low, RR = OR
Attributable risk
AR = a/(a+b) – c/(c+d)
[how much the risk is increased by the exposure]
Relative risk reduction
RRR = 1 – RR
Absolute risk reduction
ARR = c/(c+d) – a/(a+b)
Number needed to treat
NNT = 1/ARR
[Number of patients needed to be treated for one patient to benefit]
Number needed to harm
NNH = 1/AR
[Number needed to be exposed to a risk factor for 1 patient to be harmed]
Berkson bias
research participants are more unhealthy than general population
Healthy worker bias
Research participants are more healthy than general population
recall bias
Awareness of disorder affects recall (retrospective studies)
measurement bias
Miscalibrated scale
Procedure bias
subjects in different groups are not treated the same
Lead time bias:
early detection is associated with increased survival
Type 1 error
Alpha (false-positive)
H1 = False
H1 = Accepted
Type 2 error
Beta (false negative)
H1 = True
H1 = Rejected
Power
1 – beta
power and sample size
Increase sample size : increase power
t-test
two groups
ANOVA
≥3 groups
Chi-squared
≥2 groups of percentages / proportions
Correlation coefficient
r
Coefficient of determination
r^2
primary, secondary, tertiary, quaternary disease prevention
- prevention
- screening
- treatment
- unecessary treatment
Medicare
≥65
Medicaid
Very low income
Medicare: A
Hospital insurance
Medicare: B
Basic medical bill
Medicare: C
A + B delivered by approved private companies
Medicare: D
Prescription drugs
Apgar score
Appearance, pulse, grimace, activity, respiration
≥7 = good
4-6 = assist and stimulate
Serotonin nuclei in brain
Raphe nuclei