Rifampin Flashcards
1
Q
What class of antimicrobials does Rifampin belong to?
A
Rifamycins
2
Q
Is Rifampin bactericidal or bacteriostatic?
A
Both
3
Q
What species is Rifampin exclusively used in?
A
Horses
4
Q
What is the mechanism of action of Rifampin?
A
Inhibits RNA synthesize
5
Q
Why is Rifampin almost always used simultaneously with an aminoglycoside, Beta-lactum or Doxycylcine?
A
Due to widespread bacterial resistance to rifampin alone
6
Q
Interestingly rifampin may enhance what other class of drugs, making them more effective?
A
Antifungals
Amphotericin B
7
Q
What does rifampin cause as a side-effect that owners should be made aware of?
A
It causes a reddish-orange color to urine, tears, sweat, saliva and sometimes plasma
