Rheumatology / Derm Flashcards
NICE guideline >65 long term steroid therapy
oral alendronate, calcium and vit D
<65 Bone density scan
T score
Greater than 0
Reassure
Between 0 and -1.5 Repeat bone density scan in 1-3 years
Less than -1.5
Offer bone protection
shingles
dermatomal pattern
painful vesicular rash
seborrhoeic keratosis
benign skin lesion
brown/black and light tan
ABCDE rule
asymmetry, border irregularity, colour variation, diamete >6mm
bowens disease
slow growing red scaly patch -itchy
SCC
rheumatoid arthritis
raised CRP
joint swelling /tenderness
symmetric
small joint involved
polymyalgia rheumatica
> 60
rapid onset <1 month
ache/morning stiffness proximal limb muscles
ESR >40mm/hr
Creatinine kinase and emg normal
still’s disease in adults
15-25 yrs
35-46 yrs
Features:
Arthralgia
Elevated serum ferritin
rash
salmon-pink
maculopapular
pyrexia
lymphadenopathy
RF and anti nuclear antibody
methotrexate moa
inhibits dihydrofolate reductase > stops purine and pyrimidines
DNA synthesis enzyme
lowers folate level and impairs blood cell production
> WBC, RBC, platelets
ankylosing spondylitis
HLA-B27
ESR / CRP raised
Xrya of sacroiliac joints
sacroiliitis : subchondral erosions
sclerosis
squaring fo lumbar vertebrae
bamboo spine
syndesmophytes
apical fibrosis
Mx of ankylosing spondylitis
regular exercise
NSAIDs
physio
DMARDS - sulphasalazine
anti-tnf ?
reactive arthritis
HLA-B27 seronegative spondyloarthropaties
reactive / reiters
triad
pee, see, bone pain
can’t see, can’t pee, can’t climb a tree
lichen planus
immune mediated?
itchy / papular rash
> palms, soles, genitalia, flexor
white lines pattern
causes - gold, quinine, thiazineds
lotion
thin and feels light
cream
thicker than lotion
Ointment
thicker than cream
Gel
water based and often thinner than ointment
emollient
moisturise dry skin and reduce dry skin flakes
used instead od soap
30 minutes before other psoriasis treatments
Topical corticosteroid
reduces skin inflammation