Rheumatology / Derm Flashcards

1
Q

NICE guideline >65 long term steroid therapy

A

oral alendronate, calcium and vit D

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2
Q

<65 Bone density scan

A

T score
Greater than 0
Reassure

Between 0 and -1.5 Repeat bone density scan in 1-3 years

Less than -1.5
Offer bone protection

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3
Q

shingles

A

dermatomal pattern
painful vesicular rash

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4
Q

seborrhoeic keratosis

A

benign skin lesion
brown/black and light tan

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5
Q

ABCDE rule

A

asymmetry, border irregularity, colour variation, diamete >6mm

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6
Q

bowens disease

A

slow growing red scaly patch -itchy
SCC

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7
Q

rheumatoid arthritis

A

raised CRP
joint swelling /tenderness
symmetric
small joint involved

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8
Q

polymyalgia rheumatica

A

> 60
rapid onset <1 month
ache/morning stiffness proximal limb muscles

ESR >40mm/hr
Creatinine kinase and emg normal

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9
Q

still’s disease in adults

A

15-25 yrs
35-46 yrs

Features:
Arthralgia
Elevated serum ferritin

rash
salmon-pink
maculopapular

pyrexia
lymphadenopathy
RF and anti nuclear antibody

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10
Q

methotrexate moa

A

inhibits dihydrofolate reductase > stops purine and pyrimidines

DNA synthesis enzyme

lowers folate level and impairs blood cell production
> WBC, RBC, platelets

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11
Q

ankylosing spondylitis

A

HLA-B27
ESR / CRP raised

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12
Q

Xrya of sacroiliac joints

A

sacroiliitis : subchondral erosions
sclerosis

squaring fo lumbar vertebrae

bamboo spine
syndesmophytes
apical fibrosis

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13
Q

Mx of ankylosing spondylitis

A

regular exercise
NSAIDs
physio
DMARDS - sulphasalazine
anti-tnf ?

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14
Q

reactive arthritis

A

HLA-B27 seronegative spondyloarthropaties

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15
Q

reactive / reiters

triad

A

pee, see, bone pain

can’t see, can’t pee, can’t climb a tree

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16
Q

lichen planus

A

immune mediated?

itchy / papular rash

> palms, soles, genitalia, flexor

white lines pattern

causes - gold, quinine, thiazineds

17
Q
A