breast

Question 1

2WW cancer referral

Answer 1

> 30 unexplained lump w/wo pain

> 50
discharge, retraction
any other changes of cancer

Question 2

non urgent referral for breast cancer?

Answer 2

<30 unexplained lump w/wo pain

Question 3

surgical options for breast cancer include?

Answer 3

wide local excision

mastectomy

Question 4

when would you have a mastectomy?

Answer 4

multifocal tumour
central tumour
large lesion
DCIS >4cm

Question 5

tamoxifen S/E
list 3

Answer 5

increased risk of endometrial cancer
VTE

menopausal symptoms

Question 6

HER2 +
what biological therapy?

Answer 6

trastuzumab
herceptin

Question 7

when is adjuvant hormonal therapy offered?

Answer 7

hormone receptor +
tamoxifen for 5 years

anastrozole - aromatse inhibitor

ER+ve

Question 8

aromatase inhibitors S/E

Answer 8

osteoporosis

Question 9

SERM

Answer 9

selective estrogen receptor modulators

Question 10

when is adjuvant radiotherapy indicated?

Answer 10

when a wide local excision has happened instead of a mastectomy

Question 11

‘snowstorm’ sign on ultrasound of axillary lymph nodes

Answer 11

extracapsular breast implant rupture

Question 12

anastrozole MOA

Answer 12

aromatase inhibitor
androgens > oestrogen in peripheral tissues

Question 13

Trastuzumab

Answer 13

targets HER2 receptors

Question 14

breast cancer screening entails

Answer 14

mammography every 3 years

50-70 years

Question 15

surgical excision when is it indicated in fibroadenoma management?

Answer 15

> 3cm

Question 16

FEC-D chemotherapy is used for breast cancer that is?

Answer 16

node +ve

Question 17

Blood stained discharge is most likely to be associated

Answer 17

papiloma

benign tumour that grows within lactiferous duct