Chronic renal conditions

Question 1

Ix CKD

Answer 1

estimated GFR
proteinuria : ACR
haematuria
> urine dipstick
> microscopy

renal USS

BP
HBA1C
lipid profile

Question 2

g score based?

Answer 2

eGFR

Question 3

G5 ; CKD

Answer 3

<15

Question 4

G4?

Answer 4

15-29

Question 5

g3?

Answer 5

45-59

30-44

30-60

Question 6

G1?

Answer 6

> 90

Question 7

G2?

Answer 7

60-89

Question 8

Accelerated progression is a sustained decline in the eGFR

Answer 8

in 1 year

25%

15mL /min/1.73 m^2

Question 9

BP target for CKD?

Answer 9

<130/80

ACR >70

Question 10

what medication can help w disease progression of CKD?

Answer 10

ACEi
SGLT-2 inhibitors

Question 11

primary prevention of CVD statin dose?

Answer 11

atorvastatin 20mg

Question 12

renal bone disease

Answer 12

vitamin D
low phosphate diet
phosphate binders

Question 13

renal bone disease

Answer 13

High serum phosphate
Low vitamin D activity
Low serum calcium

Question 14

Osteomalacia

Answer 14

increased turnover of bones without adequate calcium supply

Question 15

Osteosclerosis

Answer 15

inadequate mineralisation of new bone due to low calcium

Question 16

Rugger jersey spine

Answer 16

spinal x-ray

sclerosis of both ends

vertebral body and osteomalacia

Question 17

PCKD

Answer 17

autosomal dominant

PKd1 gene
pkd2

Question 18

ADPKD
extrarenal manifestations

Answer 18

anuerysms
Hepatic, splenic, pancreatic, ovarian and prostatic cysts
mitral valve prolapse > MR

colonic diverticula

Question 19

oligohydramnios

Answer 19

reduced amniotic fluid volume due to reduced urine output)

an early signs of autosomal recessive pkd

Question 20

Tolvaptan role in AD PKD

Answer 20

vasopressin receptor antagonist

used in slowing development of cysts and progression to renal failure