Rheumatology Flashcards
what is pseudo gout
causes acute mono arthritis
mainly in the knee
what is seen in joint fluid aspiration of pseudo gout
positively birefringent and rhomboid shaped crystals
gout - what is it
inflammation of the joints without fever
what is seen in fluid microscopy of gout
negative birefringent
needle shaped crystals
septic arthritis - symptoms
fever and unwell patient
infectious cause
what is myasthenia gravis
immune system attacks muscle cells
causes muscle weakness
drooping of eye lids
difficulty swallowing
blurred vision
mechanism of action of methotrexate
it is a folate antagonist
people taking it can have anaemia
abnormal weakness of certain muscles
what is it
myasthenia gravis
symptoms of myasthenia gravis
drooping of eye lids
difficulty swallowing
blurred vision
what is reactive arthritis
swelling in the limbs and eyes
can be post STI
best management - oral NSAIDS
what is subacute combined degeneration of the cord
caused by severe vitamin b12 deficiency
- it causes impairment of the dorsal column and corticospinal tracts
- weakness of legs
- numbness
- loss of fine touch and propriorecption
symptoms of pages disease
bowing of the bone
raised ALP
increased osteoclast activity and then also increased osteoblast activity
this means there is disorganised bone formation and breakdown
pain the bones
what is the most common cause of oeteomyeltitis?
staphly aureus
why are medications like aspirin and thiazide like diuretics a risk factor for gout
because they reduce the excretion of uric acid which is why it builds up in the joints making gout worse
what is drug induced lupus
acne vulgaris medication like minocyline - can cause lupus
- pain in joins
ulcers in mouth
what is polymyositis
Polymyositis is an autoimmune condition in which the immune system of the body attacks.
The muscle cells which causes inflammation.
It can present with bilateral hip and shoulder weakness, raised, creatinine, kinase, and a Heliotrop, rash stiffness and pain in the fingers.
What is behcets disease
It is an autoimmune condition that can cause an inflammation around the body and
present with multiple symptoms, such as
mouth sores eye,
inflammation skin,
rashes,
aneurysms
strokes
As well as joint pain and
GI issues like diarrhoea
what is osteomalacia
- vitamin D deficiency causes softening of the bone
presents with pain - muscle weakness and bone deformaties
antibodies for Rheumatoid arthritis
Rheumatoid factor (50-90%), Anti-CCP (>95%),
antibodies for SLE
Anti-dsDNA, Anti-sm, ANA
antibodies for drug induced SLE
Anti-Histone
antibodies for sjrogens syndrome
Anti-Ro, Anti-La
antibodies for diffuse systemic scleorisis
Anti-Scl-70
antibodies for limited systemic sclerosis
Anti-Centromere
antibodies for dermatomyositis
Anti-Jo1
antibodies for Wegener’s Granulomatosis
cANCA
what is common side effect of Hydroxychloroquine used for RA
C____
colour blindness
confusion between red and green colours
what is Takayasu’s arteritis
inflammation of the aorta and its branches
symtoms of Takayasu’s arteritis
new onset headaches and weak radial pulse
antibodies for antiphospholipid syndrome
Anti-beta-2-glycoprotein I antibodies
