Cardio Pathology Flashcards
Endocarditis
- infection of the inner lining of the heart
- infection in the blood vessels coming out of the heart
Symptoms :
- fever
- chills
- small red/purple spots on the skin
- painful red lumps on fingers and toes
what is it?
Malignant hypertension
- severely high blood pressure
180/120 - can cause multiple complications and organ damage
- more vasoconstriction
- medical emergency
giant cell arteritis
- pain and stiffness in the neck
- due to inflammation of the blood vessels
- causes narrowing of arteries and reduced blood flow
pericarditis
- inflammation of the pericardium
- can be caused by virus and bacteria
symptoms:
- chest pain,
- fever
- ECG changes
Aortic Stenosis
- valve disease
narrowing of the aortic valve opening - it is followed by three symptoms
- heart failure
- syncope
- angina
- slow rising pulse
- decreased exercise tolerance
Cardiac Tamponade
- there is accumulation of fluid, blood and air in the pericardial space
- this raises intra pericardial pressure
- diastolic filling is reduced - cardiac output is reduced
Symptoms:
- tachycardia
- confusion
- chest pain
- hypotension, quiet heart sounds and raised JVP
What is Pericardiocentesis
procedure done to remove fluid that gets built up in the pericardium
Aortic Regurgitation
- the aortic valve is leaking and causes the blood to flow in the reverse direction
Mitral regurgitation
- when the mitral valve doesn’t close properly
- the blood flows backwards into the heart
Aortic Sclerosis
- thickening of the aortic valve
- but doesn’t properly block blood flow
Tricuspid Stenosis
- narrowing of the tricuspid valve
- disruption in blood flow from right atrium to right ventricle
STEMI on ECG
- new onset left bundle branch block LBBB
De Musset’s Sign
bobbing of head along with heartbeat
Quincke’s sign
pulsation of nail beds
Traube’s sign
pistol shot sound coming from femoral pulse
Muller’s sign
bobbing of the uvula
Widened pulse pressure
low diastolic pressure
ACUTE BRADYCARDIA
what is it?
-heart rate of less than 60 bpm
Causes of Bradycardia
- beta blockers
- calcium channel blockers
- hypothyroidism
- electrolyte abnormalities (hypokalaemia)
CLINICAL FEATURES OF BRADYCARDIA
- dizziness
- fatigue
- syncope
MANAGEMENT OF BRADYCARDIA
DR ABCDE
IF PATIENT IS HAVING ANY OF THESE 4: shock, myocardial ischaemia, HF or Syncope:
GIVE ATROPINE 500mcg IV
(If doesn’t work then give adrenaline 2-10mcg per minute)
how does Atropine work in managing bradycardia
blocks vagus activity to the heart so the firing to the SA node is increased
which antibiotics are associated with Long QT interval?
Macrolides
what causes raised JVP?
venous hypertension
MYOCARDITIS
What is it?
- inflammatory disease of the myocardium
CAUSES OF MYOCARDITIS
- viral infection
- auto-immune conditions
- chagus disease
- kawasaki disease: high temperature for over 5 days and swollen neck glands
SYMPTOMS OF MYOCARDITIS
- HF
- Palpitations
- Chest Pain
- Fatigue
What is heard on auscultation in pericarditis
pericardial rub
DIAGNOSING MYOCARDITIS
ST segment and T wave changes on ECG
Elevated troponin levels
ventricular dysfunction
MANAGEMENT OF MYOCARDITIS
- treat the underlying cause
- treat HF
TACHYCARDIA
what is it
heart rate >100bpm
MANAGEMENT OF TACHYCARDIA IN UNSTABLE PATIENT
EMERGENCY SYNCHRONISED DIRECT CURRENT CARDIOVERSION
MANAGEMENT OF TACHYCARDIA IN STABLE PATIENTS with REGULAR RHYTHM
Vagal manoeuvres or Valsalva manoeuvre - blow into tube
IF this fails:
GIVE ADENOSINE 6MG (over 2 seconds)
6MG
12MG
MANAGEMENT OF TACHYCARDIA IN STABLE PATIENTS with IRREGULAR RHYTHM
IF ONSET IS <48 HOURS: Flecainide
IF ONSET IS > 48 HOURS: Bisoprolol or Verapamil
SICK SINUS SYNDROME
What is given to manage tachycardia in ASTHMATIC PATIENTS
Verapamil (adenosine CANNOT be given to asthmatic patients)
when is digoxin used?
used for fast AF in patients with Heart Failure
ECG SHOWS DELTA WAVES AND SHORT PR INTERVAL
what condition is this?
Wolff-Parkinson-White syndrome
ECG SHOWS SHORT PR INTERVAL
what condition is this
Lown-Ganong-Lenine syndrome
ACUTE MYOCARDITIS
what is it
inflammation of the myocardium
FEATURES OF MYOCARDITIS
chest pain
fatigue
palpitations
TREATMENT OF ACUTE MYOCARDITIS
painkillers
antibiortics
corticosteroids - alemtuzumab
AORTIC DISECCTION
what is it
tear in the tunica intima of the aorta
blood flows between the layers making a false lumen
TWO TYPES OF AORTIC DISECCTION
type A - aortic arch and ascending aorta
type B - descending aorta
CLINICAL FEATURES OF AORTIC DISECCTION
tearing chest pain
radiates to the back
renal failure/bowel ischemia
EXAMINATION FEATURE OF AORTIC DISECCTION
feature of the blood pressure
different BP on each arm
INVESTIGATION FOR AORTIC DISECCTION
CT angiography
ECG
bloods will show raised troponin and positive D-Dimer
MANAGEMENT OF AORTIC DISECCTION
TYPE A: surgical management
TYPE B: conservative management
AORTIC REGURGITATION
what is it
incomplete closure of the AV valves
CAUSES OF ACUTE AORTIC REGURGITATION
infective endocarditis
aortic disecction
CAUSES OF CHRONIC AORTIC REGURGITATION
rheumatic heart disease
bicuspid aortic valve
Marfan’s syndrome
PRESENTATION OF ACUTE AORTIC REGURGITATION
pulmonary oedema
pallor
sweating
PRESENTATION OF CHRONIC AORTIC REGURGITATION
exertional dyspnoea
nocturnal dyspnoea
EXAMINATION FINDINGS OF AORTIC REGURGITATION
waterhammer pulse
De mussets sign
Quincke’s sign
Traube’s sign
collapsing pulse
early diastolic murmur
MAANAGEMENT OF AORTIC REGURGITATION
aortic root dilation
beta blockers
AORTIC STENOSIS
what is it
narrowing of the aortic valve
CLINICAL FEATURES OF AORTIC STENOSIS
heart failure
syncope
angina
exertional dyspnoea
EXAMINATION FINDINGS OF AORTIC STENOSIS
slow rising pulse
heaving apex beat
ejection systolic murmur on 2nd R. intercostal space
ECG FINDINGS OF AORTIC STENOSIS
increased QRS voltage
left axis deviation
WHO IS GIVEN INTERVENTION FOR AORTIC STENOSIS
- symptomatic patients
- asymptomatic patients with LVEF <50%
- asymptomatic patients with LVEF <50% who have a fall in BP during exercise
MANAGEMENT FOR AORTIC STENOSIS
transcatheter aortic valve implantation (for patients at high risk who cannot have surgery)
or
surgical aortic valve replacement
AORTIC SCLEROSIS
what is it
narrowing of the aortic valve without having any affects on the function of the valve
CLINICAL FEATURE OF AORTIC SCLEROSIS
ejection systolic murmur that doesnt radiate to the carotids
ATRIAL FLUTTER
what is it
regular, rapid atrial rate
CAUSES OF ATRIAL FLUTTER
COPD
sleep apnoea
PE
sepsis
alcohol
CLINCIAL FEATURES OF AORTIC FLUTTER
dizziness
palpitations
chest pain
ECG OF ATRIAL FLUTTER
saw tooth baseline at 300 bpm
MANAGEMENT OF ATRIAL FLUTTER
HEAMODYNAMICALLY UNSTABLE: DC cardioversion
HEAMODYNAMICALLY STABLE: rate control by beta blockers or CCB
ATRIAL FIBRILLATION
what is it
uncoordinated atrial contraction at 300-600bpm
delay at AV node so only some of the atrial contractions get passed onto the ventricles
CAUSES OF ATRIAL FIBRILLATION
CARDIAC: ischaemic heart disease, hypertension, rheumatic heart disease
NON CARDIAC: dehydration, hyperthyroidism, sepsis and PE
CLASSIFICATION OF ATRIAL FIBRILLATION
(different names for the duration)
acute <48h
paroxysmal: <7 days
persistent >7 days
permanent >7 days and doesn’t go away with cardio version
CLINICAL FEATURES OF ATRIAL FIBRIALLTION
palpitations
chest pain
shortness of breath
dizziness
MANAGEMENT OF ATRIAL FIBRILLATION
Rate control - given to those who have AF with reversible cause
eg. bisoprolol (BB)
diltiazem (CCB) and Verapamil
BB cannot be given to hypotensive patients so give DIGOXIN
MANAGEMENT OF ATRIAL FIBRILLATION BASED ON ONSET
<48 hours - DC cardioversion
>48 hours - 3 weeks on anticoagulation and then DC cardioversion
IMPORTANT DRUGS IN AF
flecainide - for younger patients
amiodarone - rate and rhythm control
sotalol - BB
CHADS2-VASC SCORE
C- congestive heart failure 1
H- hypertension 1
A- >75 2
D- diabetes 1
S-stroke 2
V- vascular disease 1
A- age <75 1
S-sex Female 1 male 0
males with score 1 and females with score 2 = anticoagulation needed
ANTICOAGULATIONS IN AF
direct oral anticoagulation - apixaban and rivaroxaban
warfarin
low molecular weight heparin
CARDIAC TAMPONADE
what is it
fluid, blood and air accumulates in the pericardial space
causes raised intra pericardial pressure and reduced cardiac output
CLINCIAL FEATURES OF CARDIAC TAMPONADE
shortness of breath
tachycardia
confusion
chest pain
abdo pain
BECKS TRIAD FOR CARDIAC TAMPONADE
hypotension
quiet heart sounds
raised JVP
RISK FACTORS OF CARDIAC TAMPONADE
pericarditis
serious injury
INVESTIGATION FOR CARDIAC TAMPONADE
ECG: low voltage on QRS complex
Chest xray: large, globular heart
ECHO: more fluid around heart
MANAGEMENT OF CARDIAC TAMPONADE
unstable patients: pericardiocentesis
stable: surgical drainage
CARDIAC MYXOMA
what is it
benign tumour in heart
CLINICAL FEATURES CARDIAC MYXOMA
fever
weight loss
nail clubbing
‘plop’ sound on auscultation
ECG FEATURES FOR COPD
right ventricular heave
HEART FAILURE MANAGEMENT
cardiac resynchronisation
MANAGEMENT OF BRADYCARDIA AFTER MI
transcutaneous pacing
MANAGEMENT OF PERICARDITIS IN POST MI PATIENTS
high dose aspirin
LEFT VENTRICULAR HYPERTROPHY IS SEEN WHEN
stable angina
CONGESTIVE HEART FAILURE: pt is already on ramipril and furosemide and bisoprolol,
what should be given now
spironolactone