Disease Profiles Flashcards
Coeliac Disease and Symptoms
protein gluten is not properly broken down - autoimmune disorder
- affects the small intestine
Symptoms: diarrhoea, abdominal distention and malabsorption
Wilsons Disease and Symptoms
- disorder of copper metabolism
- it is not metabolised properly by the liver
- copper is deposited into other organs
Addison Disease
- autoimmune disease that causes destruction to 3 layers of adrenal cortex
- destruction to corticoid hormones
Symptoms:
-fatigue, weakness, weightloss, nausea
Gout
- disease where there are recurrent attacks of arthritis
- urine deposits in joints
- causes rise in urine uric acid levels
Two types of primary gout
- enzyme deficiency so uric acid is not broken down
2. deficiency is transport of uric acid via the renal tubules
Secondary Gout
when there is a decrease in excretion of uric acid and so more is present in the body
Aneuploidy
when there is an abnormal number of chromosomes in a cell
Stable Angina and Symptoms
- narrowing of the coronary arteries
- plaque in arteries builds up and reduces blood flow to the heart
- can then lead to ischaemia of the heart as not enough oxygen is delivered
Symptoms
- central chest pain
Acute Coronary Syndrome and Symptoms
- result of sudden unpredictable distribution in coronary blood flow
- can cause ischaemia and necrosis
- caused due to plaque which can rupture and cause thrombus
Symptoms:
- chest pain that radiates to jaw, neck or arm
- shortness of breath, sweating and vomiting
Heart Failure
- the heart is unable to produce a cardiac output
-
Hypertension
- blood pressure is increased
- greater risk of stroke and heart attack
Pericarditis and Symptoms
- inflammation of the pericardium
- may be due to infection/virus
- autoimmune disease
Symptoms
- sharp retro sternal pain
- left sided pain
Constrictive Pericarditis and Symptoms
- the thickening of the pericardium
- can be caused by tuberculosis
Symptoms:
- right heart failure
- dyspnoea
Rickets
- caused due to deficiency of vitamin D
- cartilage doesn’t get calcified and bone growth is disturbed
Scurvy
- vitamin C deficiency
- collagen fibres are impaired due to lack of collagen
- can cause defects in forming capillaries