Rheumatoid Arthritis Clinical Aspects Flashcards
Define rheumatoid arthritis
Chronic, autoimmune systemic illness characterised by symmetrical peripheral arthritis and other systemic features
7 classes of RA based on the 1987 ARA criteria
1- morning stiffness 2-Arthritis of 3 or more joint areas 3-arthritis of hand joint 4- Symmetric arthritis 5- Rheumatoid nodules 6- serum rheumatoid factor 7- radiographic changes
In the RA classification define the class morning stiffness
Morning stiffness in and around joints, lasting at least 1 hour before maximal improvement
In the RA classification define the class arthritis of 3 or more joints
At least 3 joint areas simulatenously have had soft tissue swelling or fluid
In the RA classification define the class arthritis of hand joints
At least 1 area swollen in a wrist, MCP or PIP joint
In the RA classification define the class rheumatoid nodules
Subcutaneous nodules over bony prominence, or extensor surfaces, or in juxtaarticular regions
In the RA classification define the class serum rheumatoid factor
Abnormal amounts of serum rheumatoid factor
In the RA classification define the class radiographic changes
On posterioranterior hand and wrist that must include erosions, unequivocal bony decalcification
Who should be tested for RA?
Population who have: at least 1 joint with definite clinical synovitis and
With the synovitis not better explained by another disease
What score do you have to get on the 2010 EULAR/ACR classification to be diagnosed with RA?
> 5/10
Investigations for RA?
Rheumatoid factors (IgG, IgM)
Anti Cyclic Citrullinated Antibodies (anti CCP, ACPA),
X-ray
Symptoms of RA?
Pain, Stiffness, Immobility, Poor function, Systemic symptoms
Clinical signs of RA?
Swelling, tenderness, limitation of movement, redness, heat
Systemic features of RA?
Fatigue, weight loss ,anaemia,
Specific systems affected by RA?
Eyes, lungs, nerves, skin, kidneys
