REVERSIBLE CELL INURY

Question 1

2 main types of reversible injury

Answer 1

1. CELL SWELLING
2. FATTY CHANGE

Question 2

MOST COMMON & MOST IMPORTANT response to cellular injuries of all types. It’s an early manifestation of cell injury.

Answer 2

CELLULAR SWELLING

Question 3

Gross appearance of cellular swelling:

Answer 3

ORGAN- are swelling w/ round edges
TISSUE- show slight PALOR or BULGES

Question 4

in cellular swelling affected cell shows what?

Answer 4

1. ENLARGE
2. PALE CYTOPLASM
3. NUCLEUS is in normal position

Question 5

what is the staining characteristic of cellular swelling?

Answer 5

MILD- shows CLOUDY SWELLING

Question 6

Vacuoles of variable size appear in cytoplasm called ?

Answer 6

VACUOLAR DEGENERATION

Question 7

when vacuoles are severe it’s called ?

Answer 7

BALLOONING DEGENERATION

Question 8

this imply a sick cell, reversible form of injury & adaptive change may result to cell death

Answer 8

DEGENERATION

Question 9

it occur mostly on HYPOXIC, TOXIC, ,ETABOLIC . this is defines as abnormal accumulation of lipid within the cell.

Answer 9

FATTY CHANGE

Question 10

1. Lipids first enter the?
2. as a?
3. lipids are metabolized by?
4. lipids are exported from the?

Answer 10

1. HEPATOCYTES
2. FREE FATTY ACIDS
3. HEPATOCTES
4. HEPATOCYTES

Question 11

fatty acids can be synthesized from?

Answer 11

ACETATE

Question 12

some lipids are estrified to form what?

Answer 12

TG - TRIGLYCERIDES

Question 13

some lipids are synthesized to ?

Answer 13

CHOLESTEROL or PHOSPHOLIPIDS

Question 14

some lipids are oxidized for energy and produce what?

Answer 14

KETONE BODIES

Question 15

Triglycerides must be complex with a LIPID ACCEPTOR PROTEIN called?

Answer 15

APOPROTEIN

Question 16

apoprotein form this protein to be exported.

Answer 16

LIPOPROTEINS

Question 17

liver is diffusely what color when all cells are affected?

Answer 17

YELLOW

Question 18

if liver is severe, liver may?

Answer 18

FLOAT IN FIXATIVE WATER

Question 19

Histologoc appearance of fatty change:

Answer 19

1. presence of well delineated, lipid-filled vacuoles in the cytoplasm.
2. maybe single/large vacuoles (MACROVESICULAR) or multiple/small vacuoles (MICROVESICULAR)

Question 20

This special stain are used to clearly seethe lipid vacuoles, it’s a frozen section w/ an oil soluble dye called?

When it stains red, it’s lipid

Answer 20

OIL RED O