RETRO, CALICI, REO, ORTHOYXO, FILO Flashcards

1
Q

Icosahedral, enveloped virion

A

RETROVIRIDAE

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2
Q

80-130 nm

A

RETROVIRIDAE

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3
Q

Contain an RNA-dependent DNA polymerase for replication - Reverse transcription

A

RETROVIRIDAE

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4
Q

Genus: Lentivirus

A

RETROVIRIDAE

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5
Q

2 virus: HIV and HTLV 1 and 2

A
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6
Q

Genera: Norovirus, Sapovirus, Lagovirus, Vesivirus

A

CALICIVIRIDAE

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7
Q

Small, naked virus

A

CALICIVIRIDAE

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8
Q

HUMAN IMMUNODEFICIENCY VIRUS

A

RETROVIRIDAE

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9
Q

HUMAN T-LYMPHOCYTROPIC VIRUS (HTLV)

A

RETROVIRIDAE

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10
Q

NORWALK VIRUS

A

CALICIVIRIDAE

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11
Q

By by Luc Montagnier (1983)

A

HUMAN IMMUNODEFICIENCY VIRUS

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12
Q
  • Simian Virus: acquired from monkeys
A

HUMAN IMMUNODEFICIENCY VIRUS

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13
Q

: causes Acquired Immunodeficiency Syndrome

A

HIV-1

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14
Q

: restricted in West Africa

A

HIV-2

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15
Q

isolated by Robert Gallo in 1981

A

HUMAN T-LYMPHOCYTROPIC VIRUS (HTLV)

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16
Q

: causes adult acute T-cell lymphocytic leukemia, HTLV-I-associated myelopathy/tropical spastic paraparesis

A

HTLV-1

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17
Q

: linked to neurological disease

A

HTLV-2

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18
Q
  • Not associated w/ malignancies
A

HTLV-2

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19
Q

first studied from an epidemic of diarrhea in Norwalk, Ohio

A

NORWALK VIRUS

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20
Q

body fluids
sexual intercourse
parenteral (sharing of needles)
transfusion and organ transplantation
vertical transmission

A

HUMAN IMMUNODEFICIENCY VIRUS

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21
Q

sexual intercourse
parenteral
transfusion

A

HUMAN T-LYMPHOCYTROPIC VIRUS (HTLV)

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22
Q

ingestion
- highly contagious
- gastroenteritis in adults and elderly

A

CALICIVIRIDAE

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23
Q

lymphadenopathy and fever

A
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24
Q

opportunistic infections

A
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25
malignancies
26
wasting
27
AIDS
28
dementia
29
- Weight loss, malaise - Pneumocystis carinii (pneumonia) - Herpes, diarrhea - Alzheimer’s disease
HUMAN IMMUNODEFICIENCY VIRUS
30
- Antiretroviral therapy: increases CD4 value of
HUMAN IMMUNODEFICIENCY VIRUS
31
o: normal o: with HIV
400 <200
32
AIDS was first described on June 5, 1981
HUMAN IMMUNODEFICIENCY VIRUS
33
approx. 38 million infected worldwide (2019) prevalent in Africa
HUMAN IMMUNODEFICIENCY VIRUS
34
8500 per day
HUMAN IMMUNODEFICIENCY VIRUS
35
1.8M children (vertical transmission)
HUMAN IMMUNODEFICIENCY VIRUS
36
Prevalence in 15 - 24 y/o.
HUMAN IMMUNODEFICIENCY VIRUS
37
occurrence of rare diseases
HUMAN IMMUNODEFICIENCY VIRUS
38
fewer than 200 CD4 lymphocytes per uL of blood
HUMAN IMMUNODEFICIENCY VIRUS
39
ELISA (screening), western blot (confirmatory)
HUMAN IMMUNODEFICIENCY VIRUS
40
mechanical prophylaxis, not sharing of needles, screening blood
HUMAN IMMUNODEFICIENCY VIRUS
41
no vaccines yet
HUMAN IMMUNODEFICIENCY VIRUS
42
"cocktail" - Malaria, Hepa B, Hepa C
HUMAN IMMUNODEFICIENCY VIRUS
43
good hygiene water purification sewage treatment
CALICIVIRIDAE
44
Helical, envelop, 75-125 nm
ORTHOMYXOVIRIDAE
45
with lipid bilayer envelope with surface glycoproteins (Hemagglutinin (for attachment) and Neuraminidase)
ORTHOMYXOVIRIDAE
46
enveloped, helical, single stranded
FILOVIRIDAE
47
800-1000 nm
FILOVIRIDAE
48
forms long filaments which sometimes curve back upon themselves
FILOVIRIDAE
49
EBOLA VIRUS
FILOVIRIDAE
50
MARBURG VIRUS
FILOVIRIDAE
51
INFLUENZA A, B, AND C
ORTHOMYXOVIRIDAE
52
ROTAVIRUS
REOVIRIDAE
53
spherical with prominent spikes
REOVIRIDAE
54
acquires and loses its envelope during replication
REOVIRIDAE
55
Disease: infantile gastroenteritis
REOVIRIDAE
56
- 50% of diarrhea among children
REOVIRIDAE
57
Severity: ++++
A
58
Severity: ++
B
59
Severity: +
C
60
Animal Reservoir: Yes
A
61
Animal Reservoir: No
B, C
62
Antigenic Changes: shift, drift
A
63
Antigenic Changes: drift
B, C
64
: first reported outbreak came from Congo in 1976 near the Ebola river (highest fatality rate)
EBOLA VIRUS
65
: first isolated in Marburg, Germany
MARBURG VIRUS
66
fecal-oral, self-limiting
REOVIRIDAE
67
droplet spray
ORTHOMYXOVIRIDAE
68
pattern shows school children bringing home the disease infecting other family members
ORTHOMYXOVIRIDAE
69
Pathogenesis: viruses attack the macrophages and liver cells
FILOVIRIDAE
70
internal organs become jelly like in consistency uncontrolled bleeding under the skin
FILOVIRIDAE
71
glycoprotein produced by the virus prevents cells to adhere to each other allowing blood to leak out of the blood vessels headache and severe fever
FILOVIRIDAE
72
epidemics last for 3 to 6 weeks
ORTHOMYXOVIRIDAE
73
90% fatality rate
FILOVIRIDAE
74
epidemics stop when there is not enough people to infect
FILOVIRIDAE
75
person to person
FILOVIRIDAE
76
via contaminated fluid (blood)
FILOVIRIDAE
77
Outbreak in Africa
FILOVIRIDAE
78
vaccine (for monkeys)
FILOVIRIDAE
79
supportive care
REOVIRIDAE
80
RotaShield vaccine
REOVIRIDAE
81
- Summer, near drainage
REOVIRIDAE