ARENAVIRIDAE, ASTROVIRIDAE, CORONAVIRIDAE Flashcards
• Enveloped
ARENAVIRIDAE
• Irregular-shaped capsid
ARENAVIRIDAE
• 2 circular segments
ARENAVIRIDAE
• single-stranded RNA genome
ARENAVIRIDAE
• measures 50 -300 nm
ARENAVIRIDAE
• Virion is non -enveloped
ARENAVIRIDAE
• Resistant to lipid solvents and trypsin
ARENAVIRIDAE
• Contain single stranded, positive sense RNA
ASTROVIRIDAE
• Single stranded
CORONAVIRIDAE
• Enveloped with helical capsid
CORONAVIRIDAE
• Envelope forms a crown-like
CORONAVIRIDAE
• Halo around the capsid
CORONAVIRIDAE
● Electron microscope: sandy and granular
ARENAVIRIDAE
● Electron microscope: star-shaped polyhedral capsid
ASTROVIRIDAE
● largest genome among RNA viruses
CORONAVIRIDAE
● Electron microscopy: distinctive club shaped projections on their surface
CORONAVIRIDAE
● bite of infected mice and rats (urine, saliva, dropping)
ARENAVIRIDAE
2 Categories of Arenaviruses
- New World Arenaviruses
- Old World Arenaviruses
: Western Hemisphere - North and South America
- New World Arenaviruses
: a severe or fatal hemorrhagic fever found in Bolivia
- New World Arenaviruses - Chapare virus
: found in Venezuela
- New World Arenaviruses - Guanarito virus
: Eastern Hemisphere - Africa, Europe, and Asia
- Old World Arenaviruses
: can cause mild to severe disease; West Africa
- Old World Arenaviruses - Lassa fever
: fatal hemorrhagic fever; Southern Africa
- Old World Arenaviruses - Lujo
: both the Western and Eastern Hemisphere
- Old World Arenaviruses - LCMV
● major cause of diarrhea in the young, elederly, and immunocompromised patient
ASTROVIRIDAE
● first discovered in 1975, the human astrovirus type (HAstV-1)
ASTROVIRIDAE
● has expanded to include two more human clades and numerous mammalian and avian-specifc genotypes.
ASTROVIRIDAE
asymptomatic
ARENAVIRIDAE
fever
ARENAVIRIDAE
prostration
ARENAVIRIDAE
headache and vomiting
ARENAVIRIDAE
meningitis
ARENAVIRIDAE
hemorrhagic fever
ARENAVIRIDAE
ubiquitous in children
ASTROVIRIDAE
minority of childhood diarrheas
ASTROVIRIDAE
mild to moderate respiratory illness and recover without requiring special treatment.
CORONAVIRIDAE
Older people, and those with underlying medical problems like cardiovascular disease, diabetes, chronic respiratory disease, and cancer are more likely to develop serious illness
CORONAVIRIDAE
15% of coldlike infections in adults
CORONAVIRIDAE
higher seroconversion rates have been seen in children
CORONAVIRIDAE
few CoVs are responsible for a small percentage of pediatric diarrhea cases
CORONAVIRIDAE