6-SUBCUTANEOUS-FUNGI Flashcards
- MOT: trauma or pricking of the skin (ulceration, crusted, hard skins)
SUBCUTANEOUS MYCOSES
- Affects the extremities or feet
SUBCUTANEOUS MYCOSES
- Habitat: soil
SUBCUTANEOUS MYCOSES
- Mainly caused by dematiaceous fungi (slowly groeing fungi found in soil and vegetation)
SUBCUTANEOUS MYCOSES
Pseudoallescheria boydii, Exophiala, Acremonium, and Madurella
MYCETOMA
Granulomatous infection of the subcutaneous tissue causing cutaneous abscesses
MYCETOMA
o “(?)” – swollen tumor- like areas with sinuses for drainage
oma
Most infections are found in Africa
MYCETOMA
Exudate: red, yellow, or black granules
MYCETOMA
Fonsecaea pedrosoi, Phialophora, Cladosporium, Exophiala, and Wangiella
CHROMOBLASTOMYCOSIS
- Localized infection characterized by verrucoid (wartlike) crusted nodules of the skin
CHROMOBLASTOMYCOSIS
- Painless without secondary infection
CHROMOBLASTOMYCOSIS
- Affects the feet or lower legs
CHROMOBLASTOMYCOSIS
Seen in tropical areas of the world
CHROMOBLASTOMYCOSIS
Sclerotic bodies
CHROMOBLASTOMYCOSIS
- infection caused by dematiaceous fungi
PHAEHYPHOMYCOSIS
- Bipolaris, Curvularia, Phialophora, and Alternaria
PHAEHYPHOMYCOSIS
- Superficial or subcutaneous infection that can become systemic
PHAEHYPHOMYCOSIS
o Endocarditis
PHAEHYPHOMYCOSIS
o Brain abscesses
PHAEHYPHOMYCOSIS
- Sporothrix schenckii
SPOROTRICHOSIS
- Dimorphic fungi (either mold or
yeast)
SPOROTRICHOSIS
“(?)” – obtained from infected roses
rose gardener’s disease
Endemic among rose gardeners
SPOROTRICHOSIS
- Yeast: Agar with Blood at 35oC
SPOROTRICHOSIS
- Mold: SDA or PDA at RT
SPOROTRICHOSIS
- nodular lesions that suppurate, ulcerate and drain
SPOROTRICHOSIS
- Tree-like
Cladosporium
- chains branch from a conidium
Cladosporium
- with vase-shaped phialide arising from a conidiophore
Phialophora
- resembles a body builder
Rhinocladiella
- with primary, secondary and tertiary conidia
Rhinocladiella
- rarely seen
Rhinocladiella
chromoblastomycosis
Cladosporium carionii
dark with jet black reverse
Cladosporium carionii
brown sclerotic bodies/medllar
bodies
Cladosporium carionii
cauliflower-like
Cladosporium carionii
- mycetoma, phaeohyphomycosis
Exophiala jeanselmei
- Dimorphic
Exophiala jeanselmei
chromoblastomycosis, phaeohyphomycosis
Fonsecaea pedrosoi
-(?) – causes elephantiasis
Secondary infection
chromoblastomycosis, phaehyphomycosis
Phialophora verrucosa
- Hyphae: dark septate
Cladosporium carionii
- Conidia: cladosporium type
Cladosporium carionii
- eumycotic mycetoma
Pseudallescheria boydii
- fast-grower
Pseudallescheria boydii
- perfect fungus (teleomorph or
sexual)
Pseudallescheria boydii
o with white or light colored granules on drainage
eumycotic mycetoma
Fungoma: tumor-like mass in the lungs
Pseudallescheria boydii
- Hyphae: hyaline septate and loosely arranged
Pseudallescheria boydii
- Conidia: lollipop shaped or lemon shaped annelloconidia on annellides
Pseudallescheria boydii
- Cleistothecia : sexual ascospores; enmeshed with hyphae
Pseudallescheria boydii
o Globus ascocart
Pseudallescheria boydii
-Scedosporium apiospermum:
asexual/anamorph form
Pseudallescheria boydii
- Hyphae: septate branched with bends and tortuous ends
Exophiala jeanselmei
- Conidia: annelloconidia ; attached to an annellide then to an annellophore; with vermiform granules (black pepper) on direct examination
Exophiala jeanselmei
- sporotrichosis
Sporothrix schenckii
- ulcers and abscesses along the
lymphatic channels
Sporothrix schenckii
- Rose gardener’s disease
Sporothrix schenckii
- Dimorphic fungi
Sporothrix schenckii
- white to black
Sporothrix schenckii
- Yeast form: cigar shaped or asteroid
bodies
Sporothrix schenckii
- Mold form: flowerette or daisy like
conidia
Sporothrix schenckii
- Hyphae: ropelike hyaline septate
Sporothrix schenckii
- Conidia: conidiophores arise at right
angles
Sporothrix schenckii
- Hyphae: dark brown septate hyphae
Fonsecaea pedrosoi
- Conidia: all three types
Fonsecaea pedrosoi
- phaeohyphomycosis
Wangiella dermatitidis
- Dimorphic fungi
Wangiella dermatitidis
- Hyphae: septate and branched with tortuous twists and turns
Wangiella dermatitidis
- Conidia: phialophora type with ovoid and unicellular conidia; attached to flask shaped phialide and without collarett
Wangiella dermatitidis
- Hyphae: dark septate hyphae
Phialophora verrucosa
- Conidia: Phialophora
Phialophora verrucosa
- with distinct swollen center and
collarette
Phialophora verrucosa
cerebral phaeohyphomycosis
Xylohypha bantiana
- Hyphae: septate
Xylohypha bantiana
- Conidia: cladosporium (tree-shaped
blastoconidia) type with
blastoconidia
Xylohypha bantiana
- Conidiophores: with poor posture
Xylohypha bantiana
- Rarely seen
Xylohypha bantiana
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