Respiratory System 1 Flashcards

1
Q

functions of the respiratory system?

A
  • gas exchange: take in o2, eject co2
  • regulate blood pH: alters co2 levels
  • voice production: air movement past vocal cords
  • olfaction: in nasal cavity
  • innate immunity: physical protection of blood
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2
Q

upper respiratory system includes…

A
  • nose
  • nasal cavity
  • pharynx
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3
Q

lower respiratory system includes…

A
  • larnyx
  • trachea
  • bronchi
  • lungs
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4
Q

what are the functions of the nose?

A
  • passageway for air
  • cleans air
  • humidifies + warms air
  • smell
  • along with paranasal sinuses, = resonating chambers for speech
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5
Q

what is the pharynx?

A

common passageway for respiratory system

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6
Q

nasopharynx

A
  • auditory tubes empty here
  • elevated when swallow + held open when sneeze
  • pharyngeal tonsils located here
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7
Q

what is the soft palate?

A

floor of nasopharynx, posterior portion = uvula

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8
Q

oropharynx

A

extends from uvula to epiglottis

  • oral cavity opens into oropharynx
  • lined with stratified epithelium
  • 2 tonsils
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9
Q

laryngopharynx

A

extends from epiglottis to oesophagus

food + drink

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10
Q

functions of the larynx

A
  • maintains open air tube
  • voice production
  • allow us to hold breath
  • closes air tube when swallow —> prevents food from entering trachea
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11
Q

what is the larynx

A

complex assortment of cartilages

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12
Q

trachea

A

= windpipe

  • connective tissue + smooth muscle, supported by cartilage
  • cartilage protects trachea + maintains OPEN airway; smooth muscle constricts airway
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13
Q

what are the effects of smoking on the trachea?

A
  • destroyed ciliated cells
  • mucous collects
  • microorganisms not ejected
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14
Q

bronchi

A
  • symmetrical branches from trachea

- extensions with same tissue types

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15
Q

parasympathetic division

A

innervates bronchial smooth muscle + submucosal glands

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16
Q

what does the stimulation of parasympathetic division cause?

A
  • bronchial smooth muscle contraction
  • inc mucuc secretion

effects mediated by M3 ACh receptors

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17
Q

sympathetic division

A

no innervation of bronchial smooth muscle

supplies submucosal glands + smooth muscle of blood vessels

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18
Q

what does stimulation of sympathetic division cause?

A
  • bronchial smooth muscle relaxation
  • decreased mucus secretion
  • inc mucociliary clearance

mediated via beta2-adrenoreceptors
neuronally rel by NA

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19
Q

lung structure

A
  • divided into lobes (R=3, L=2) divided by septa
  • bronchioles divide unto alveolar ducts + alveoli
  • as bronchi + bronchioles divide, cartilage dec + smooth muscle inc
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20
Q

during exercise, what happens to the diameter of the alveolar duct?

A

inc

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21
Q

during an asthma attack, what happens to the diameter of the alveolar duct?

A

dec

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22
Q

describe the respiratory membrane?

A
  • thin fluid layer lines alveolus
  • alveolar epithelium = simple squamous
  • interstitial space = THIN
  • capillary epithelium = simple squamous
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23
Q

what is inspiration + expiration caused by?

A

changes in thoracic volume

produces change in air pressure in lungs

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24
Q

muscle of expiration include…

A
  • abdominals

- internal intercostals

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25
muscles of inspiration include…
- diaphragm | - external intercostals (scalenes etc)
26
at the end of expiration, what does Patm =
Palv no air flow
27
during inspiration, what does Patm =
> Palv inc thoracic vol dec Palv air flows into alveoli
28
at the end of inspiration, what does Patm =
Palv no air flow
29
during expiration, what does Patm =
< Palv dec thoracic vol = inc pressure in alveoli air flows out of lungs
30
premature babies lack surfactant, what does this put them at a risk of?
respiratory distress syndrome
31
when does lung compliance and ventilation decrease?
when lungs become diseased and fibrotic (COPD)
32
passive expiration occurs due to...
lung recoil
33
what are the 2 causes of lung recoil?
- elastic fibres in connective tissue of lung | - surface tension of h2o molecules pull on alveolar walls
34
surfactant …. lung recoil
opposes
35
what is a surfactant secreted by and what does it consist of?
by cells of alveolar epithelium lipoproteins + interferes with surface tension produced by water
36
what is a surfactant?
detergent like substance which dec surface tension
37
define tidal volume
vol of air inspired/expired during normal inspiration/expiration
38
define inspiratory reserve vol
amount air inspired forcefully after inspiration of normal tidal volume
39
define expiratory reserve vol
amount air expired forcefully after expiration of normal tidal vol
40
define residual vol
vol air remaining in respiratory passages + lungs after most forceful expiration
41
define inspiratory capacity
tidal vol plus inspiratory reserve vol
42
define functional residual capacity
expiratory reserve vol plus residual vol
43
define vital capacity
sum of inspiratory reserve vol, tidal vol, expiratory reserve vol
44
define total lung capacity
sum of inspiratory + expiratory reserve vol + tidal vol + residual vol
45
what is vital capacity also known as?
max amount air one can forcefully inspire + expire
46
what is vital capacity, influenced by?
- age - sex - body size - training
47
what is the dead space?
some inspired air never contributes to gas exchange
48
what is the anatomical dead space?
vol of conducting zone conduits (~150ml)
49
what is the alveolar dead space?
alveoli that cease to act in gas exchange due to collapse/obstruction
50
what is the total dead space?
sum of anatomical dead space + alveolar dead space
51
what is a spirometer?
pulmonary function test instrument used to measure respiratory vol + capacities
52
what can spirometry distinguish between?
- obstructive pulmonary disease (bronchitis) | - restrictive disorders (TB_
53
what is minute ventilation?
total amount of gas flow into/out of respiratory tract in 1 min
54
what is forced vital capacity? (FVC)
gas forcibly expelled after taking deep breath
55
what is forced expiratory volume? (FEV)
amount gas expelled during specific time intervals of FVC
56
inc in TLC, FRC, RV may show signs of ...
obstructive disease
57
dec in VC, TLC, FRC, RV may show signs of ...
restrictive disease
58
define alveolar ventilation rate?
flow of gases into/out of alveoli during certain time
59
formular to find AVR (ml/min)?
frequency (breaths/min) X (TV-dead space) ml/breath
60
what is dead space normally in alveolar ventilation?
constant
61
rapid, shallow breathing …. AVR
dec