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Pharmacology > Respiratory drugs > Flashcards

Respiratory drugs Flashcards

1
Q

Beta 2 agonist examples

A

Salbutamol- SABA
Terbutaline- SABA
Formoterol- LABA
Salmeterol- LABA

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2
Q

Beta 2 agonist mechanism of action

A

Activation of B adrenergic receptors leading to relaxation of smooth muscle in the lung
dilation and opening of the airway

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3
Q

Uses of Beta 2 agonists

A

Asthma

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4
Q

Side effects of Beta 2 agonists

A 
Headache
Anxiety
Nausea
Muscle tremors
Nervousness palpitations
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5
Q

Examples of anti-muscarinics

A

Ipratropium bromide

Tiotropium bromide

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6
Q

Anti-muscarinic mechanism of action

A

Blocks muscarinic acetylcholine receptors- m3
bronchodilator
M3 receptor agonist

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7
Q

Anti-muscarinic uses

A

Severe asthma

COPD

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8
Q

Anti-muscarinic side effects

A

dry mouth
urinary retention
Glaucoma

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9
Q

methlyaxthines examples

A

Theophylline

Aminophylline

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10
Q

Methylanxthines mechanism of action

A

antagonise adenosine receptors
inhibit phosphodiesterase and increase cAMP
Adenosine antagonist

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11
Q

Methylanxthines uses

A

Asthma

COPD

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12
Q

Methylanxthines side effects

A 
Nausea
Headache
Reflux
Toxicity
Arrhythmias and fits
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13
Q

Corticosteroid examples

A

Beclomethosone Dipropionate
Bedenside
Fluticasone

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14
Q

Costicosteroid mechanism of action

A

Mimic the effect of hormones in the body which suppress inflammation and reduce activity of the immune system

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15
Q

Uses of corticosteroids

A

Asthma
Allergic reactions
Arthritis

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16
Q

Side effects of corticosteroids

A 
Weight gain
osteoporosis
hypertesnion
diabetes
glaucoma 
thinning of skin
bruising
17
Q

Leukotriene receptor antagonist examples

A

Montelukast

Zafirlukast

18
Q

Leukotriene receptor antagonist mechanism of action

A

Leukotrienes are released by mast cells and eosinophils and induce bronchoconstriction, mucus secretion, mucosal oedema and inflammatory recruitment cells,
LRTAs block the effect of cyteinul leukotrienes in the airways at the CysLT1 receptor

19
Q

Leukotriene receptor antagonist uses

A

Mast cell disorders

Asthma

20
Q

Leukotriene receptor antagonist side effects

A 
Angioedema
dry moiuth
anaphylaxis
athragia
fever
GI disturbance
Nightmares

Pharmacology (13 decks)

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