Infection drugs

Question 1

Penicillin examples

Answer 1

Penicillin
Amoxicillin
Flucloxacillin

Question 2

Penicillin mechanism of action

Answer 2

B lactam antibiotics

selectively interfere with synthesis of bacterial cell wall

Question 3

Penicillin uses

Answer 3

Gram positive
Amoxicillin- gram positive and negative
otitis media, meningitis, pneumonia etc

Question 4

Penicillin side effects

Answer 4

Resistance
allergic reactions
hypersensitivity

Question 5

Tetracycline examples

Answer 5

Dooxycycline

Question 6

Tetracycline mechanism of action

Answer 6

Inhibits synthesis of proteins

binds to 30s ribosome of the bacteria and prevents attachment of tRNA to RNA

Question 7

Tetracycline uses

Answer 7

Broad spectum
Gram positive
Pneumonia, Chlamydia

Question 8

Tetracycline side effects

Answer 8

GI side effects
teeth discolouration
Foetal development

Question 9

Macrolides examples

Answer 9

Clarithromycin

Question 10

Macrolides mechanism of action

Answer 10

Inhibits synthesis of proteins

Bind to 50s and block polypeptides exit tunnel to prevent chain elongation

Question 11

Macrolides uses

Answer 11

Atypical respiratory

Gram positive

Question 12

Macrolides side effects

Answer 12

GI side effects

tinnitus

Question 13

Cephalosporin examples

Answer 13

Cefactor
Cefotaxmine
Aztreonam

Question 14

Cephalosporin mechanism of action

Answer 14

B lactam antibiotic

selectively interfere with synthesis of bacterial cell wall

Question 15

Cephalosporin uses

Answer 15

Respiratory tract infection
skin infections
urinary tract infections

Question 16

Cephalosporin side effects

Answer 16

GI upset
thrush
blood abnormalities

Question 17

Aminoglycoside examples

Answer 17

gentamicin

Neomycin

Question 18

Aminoglycoside mechanism of action

Answer 18

Irreversible inhibition of protein synthesis

Question 19

Aminoglycoside uses

Answer 19

Gram negative

Question 20

Aminoglycoside side effects

Answer 20

nephrotoxic, ototoxic, NMT blockade, pregnancy category C

Question 21

Vancomycin mechanism of action

Answer 21

Tricylicic glycopeptide

inhibits synthesis of bacterial cell wall phospholipids

Question 22

Vancomycin antibiotics

Answer 22

C diff
gram possitive
multi drug resistant organisms
B lactam allergy people

Question 23

vancomycin side effects

Answer 23

allergic reaction
low blood pressure
indigestion
itching dizziness

Question 24

Antifungal drug examples

Answer 24

Nystatin
Clotrimazole
Amphotericin

Question 25

Antifungal drug examples

Answer 25

Binds to ergosterol, part of the fungal cell membrane and forms pores causing k+ leakage, acidification and death of the fungus

Question 26

Antifungal drug uses

Answer 26

Fungus

Question 27

Antifungal drug side effects

Answer 27

Loss of appetite
Sickness
Temperature, chills and headache

Question 28

Antiprotozoal drug examples

Answer 28

Antimalarial e.g. chloroquine, metronidazole

Question 29

Antiprotozoal drug mechanism

Answer 29

Forming toxic complexes with feritopoorphim IX that damage the membrane of the parasite

Question 30

Antiprotozoal drug uses

Answer 30

Antimalarials

Question 31

Antiprotozoal drug side effects

Answer 31

GI side effects, mouth sees, rash, balance and walking problems

Question 32

Anti TB drugs examples and side effects

Answer 32

Ethambutol
Isoniazid
Pyrazinamide
Rifampicin
can cause hepatotoxicity, neuritis, GI and allergic reactions

Question 33

Antiviral examples

Answer 33

Aciclovir
Valaciclovir
Valganiciclovir
Zanamivir
Oseltamivir

Question 34

antiviral mechanism of action

Answer 34

Neurominidase inhibitor

block release of newly assembled influenza vironions from host cell

Question 35

Antiviral drug uses

Answer 35

Influenza A and B

Question 36

Antiviral drug side effects

Answer 36

GI side effects
runny nose
cough
behavioural changes