Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Endocrine drugs > Flashcards

Endocrine drugs Flashcards

1
Q

Insulin examples

A 
Ultrafast acting- Aspart
Rapid acting- Norarapid
Short acting- Actrapid, humulin S
Intermediate acting- Isophane inulin
Long acting- Glargine, Insulin Degludec
Very long acting- Deglugec
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Insulin mechanism of action

A

Stimulates uptake of glucose into the liver, muscle and adipose
Decrease hepatic glucose output via inhibition of Gluconeogenesis
Promotes fat uptake

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Insulin uses

A

Diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Insulin side effects

A

Hypoglycemia
Lipodystrophy
Painful injections
Insulin allergies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Biguanide examples

A

Metformin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Biguanide mechanism of action

A

Reduces insulin resistance so increases glucose in tissues
Decrease hepatic glucose production
limits weight gain
decrease CVS events

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Biguanide uses

A

Diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Biguanide side effects

A

GI symptoms
Lactic acidosis
B12 deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Sulphonylureas examples

A

Gliclazide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Sulphonylureas mechanism of action

A

Stimulate beta cells to release insulin, decrease microvascular risk
ATP sensitive K+ channel blocker

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Sulphonyureas uses

A

Diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Sulphonyureas side effects

A

Weight gain

Hypoglycemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Thiazolidinediones examples

A

Pioglatazone

Rosiglatazone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Thiazolidinediones mechanism of action

A

PPARY receptor agonist

increase insulin sensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Thiazolidinediones uses

A

Diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Thiazolidinediones side effects

A

Cardiovascular concerns, weight gain, fluid retention, heart failure, bone metabolism, bladder cancer

17
Q

GLP1 examples

A

Exenatide

Liraglutide

18
Q

GLP1 mechanism of action

A

Alternate hormone system influencing glucose metabolism

Increase insulin from beta cells and decrease glucagon from alpha cells

19
Q

GLP1 uses

A

Diabetes

20
Q

GLP1 side effects

A

GI upset, reflux, hypoglycaemia, pancreatitis, painful to inject

21
Q

DPP4 inhibitor examples

A

Sitagliptin

Linagliptin

22
Q

DPP4 inhibitor mechanism of action

A

inhibits DPP4 activity

increase GLP1 concentrations

23
Q

DPP4 inhibitor uses

A

Diabetes

24
Q

DPP4 inhibitor side effects

A

GI symptoms
Pancreatitis
Hypoglycaemia

25
Q

SGLT-2 Inhibitor examples

A

Canagliflozin

Dopaglifozin

26
Q

SGLT-2 inhibitor mechanism of action

A

Blocks sodium glucose cotransporter

prevents kidney from reabsorbing glucose back into the blood

27
Q

SGLT-2 inhibitor uses

A

Diabetes

28
Q

SGLT-2 inhibitor side effects

A

Kidney failure, Hyperkalaemia, ketoacidosis and increased cholesterol

Pharmacology (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions